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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. FPGA-Based End-Station Security for High-Performance Networking

    SBC: Acadia Optronics, Llc            Topic: 52b

    Traditional enterprise cyber-security methods are inadequate to address the increasing number of threats, particularly within larger and higher-performance networks. Several government and third party organizations report consistent failures within corporate and federal, state, and local government networks. A key point of failure in securing these networks is the centralized security architectu ...

    SBIR Phase II 2010 Department of Energy
  2. Automated Systems for Detection and Molecular Characterization of Circulating Tum

    SBC: ADVANCED CELL DIAGNOSTICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The detection and enumeration of circulating tumor cells (CTCs) has the potential to become a very powerful tool in cancer diagnosis and treatment. However, current technologies for CTC detection are not yet established in routine clinical practice. One reason is that CTCs are present in blood at an extremely low concentration of one in 10 million white blood c ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. A Scalable Distributed Client Based Meta Search and Discovery Infrastructure

    SBC: Weblib, Llc            Topic: 64a

    Web searching has become a ubiquitous and indispensable activity for a wide spectrum of human endeavors. The success of Google and its competitors depends on extensive software and network infrastructures and costly hardware. Federated search engines, such as Science.gov, WorldWideScience.org and ScienceEducation.gov also run on powerful, albeit much smaller, server clusters that connect to divers ...

    SBIR Phase II 2010 Department of Energy
  4. Novel Targeted Therapy for Breast Cancer

    SBC: A&G PHARMACEUTICAL, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Breast cancer remains one of the top three cancers to affect and cause mortality in women. Major shortcomings with current treatment are the high level of side effects induced in patients and insufficient efficacy, particularly for patients with metastatic disease. Targeted cancer therapy is designed to treat only the cancer cells and minimize damage to healthy ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  5. PredicTOR: predicting patient response to mTOR pathway inhibitors prior to treatm

    SBC: 20 20 Genesystems Inc            Topic: NCI

    DESCRIPTION (provided by applicant): The promise of personalized medicine relies on the development of diagnostic tests to categorize patients within small cohorts who will benefit from specific treatments. 20/20 GeneSystems, Inc. (20/20) is a small business concern focused on the development of diagnostics for personalized medicine. Towards this end, 20/20 has developed, with the support of the N ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. Targeted tumoricidal bacteria

    SBC: ANTICANCER, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): We have developed an effective bacterial cancer therapy strategy by targeting viable tumor tissue by using Salmonella typhimurium auxotrophs that we have generated which grow in viable as well as necrotic areas of tumors. However, the auxotrophy severely restricts growth of these bacteria in normal tissue enabling them to be used for cancer treatment. The S. ty ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Liquid Array Protein Assay Platform

    SBC: ARRAYOMICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The aim of this project is to develop and optimize our novel particle-based microarray platform, ArrayableESP, for application to high multiplex (50- to 2000-plex) proteomic analysis of human serum samples. ESPs are optically-encoded microfabricated particles that can be manipulated using magnetic force. They are manufactured on commercially available photolith ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Sustained Release Depot Olanzapine

    SBC: AURITEC PHARMACEUTICALS, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): The long-term goal of this research is to minimize morbidity due to non-adherence to outpatient antipsychotic-antimanic therapy with olanzapine. Olanzapine is currently a mainstay of treatment for psychotic disorders and mania. Its elimination half-life of (ca. 30 h in humans) is appropriate for once-daily oral dosing. Most psychotic and manic-depressive disord ...

    SBIR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Physical Layer Network Management Tools Based on Automated Fiber Optic Patch-Panels

    SBC: Telescent Inc.            Topic: 52d

    Low cost, massively scalable, automated fiber optic patch-panels are the key network elements of the future, enabling software driven control, monitoring and mapping of the fiber optic physical network layer. Physical layer automation promises to dramatically improve the reliability and agility of high bandwidth communications services. Considering that the cost to operate today

    SBIR Phase II 2010 Department of Energy
  10. RFID Overlay Network for Automated Discovery at the Physical Network Layer

    SBC: Telescent Inc.            Topic: 52d

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    SBIR Phase II 2010 Department of Energy
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