Award Data

PROJECT SUMMARY / ABSTRACTThe objective of this Phase II proposal is to further develop a novel device for ocular anesthesia based on thermo-electric cooling. Intravitreal injection therapy (IVT) is one of the most commonly performed procedures in all of medicine, with approximately 7 million injections in the USA in 2016. Ocular anesthesia is required, both for patient safety and for tolerability ...

Project Summary/Abstract Prospective evaluation of a surgical solution for breast cancer-associated lymphedema The proposed project will complete remaining key research and technology requirements that are needed to commercialize a ground-breaking interventional device for treating secondary lymphedema -- a chronic and debilitating disease that currently has no cure and impacts an estimated 15-30% ...

The U.S. Air Force is interested in developing hypersonic vehicles including reusable transport aircraft, cruise missiles, and unmanned systems. Hypersonic flight regimes result in multifaceted and very difficult design challenges that can be encapsulated into an aerothermoelastic problem, which is a complex interaction of structural, thermal, and aerodynamic mechanisms. When a flexible structural ...

Many of the US Department of Defense (DOD) electrical connectors, back-shells and components currently contain cadmium (Cd).Cadmium is a known carcinogen.Furthermore, the cadmium is typically conversion coated with a hex-chromate which is also hazardous.Both the cadmium plating process and its subsequent conversion coating have been proven to be toxic (unlike other processes such as chromium plati ...

3D printing has recently taking a lead role as a potential solution for future manufacturing. However, there are still many problems and limitations to the technology for cost effective high resolution, high throughput manufacturing.Derived from the SBIR Phase I effort, Digibeam is presenting an innovative solution using a different beam and growth process that directly addresses both resolution a ...

To address the Air Force need for advanced radar characterization of fighter aircraft, Physical Optics Corporation (POC) is developing a new Near Field Scanner (NeFS) based on novel RF/microwave sensing and scanning technologies. Specifically, innovations in sensor miniaturization and broadband functionality, combined with an innovative 3D scanning platform, enable NeFS to measure near-field radia ...

To address the Air Force need for an automated target recognition (ATR) capability that uses Light Detection and Ranging (LIDAR), Physical Optics Corporation (POC) proposes to advance the development of the Highly Parallel LIDAR-based Automated Target Recognition (PLATR) system, which was proven feasible in Phase I. PLATR is based on an innovative combination of target isolation, target pose estim ...

The QuantiDNA RadTox System is a unique, patented technology that measures tissue damage shortly following injury using cell-free DNA from a drop of blood. Premised on murine and primate studies showing circulating DNA is logarithmically increased with whole-body radiation dose, RadTox has the potential to overcome many of the species-specific challenges faced by biomarker panels. The phase I SBIR ...

This proposal is to develop a novel slide based proximity assay platform to quantify protein phosphorylation on tissues. The novelty of this assay platform is derived from the use of the quantum dot with two emission peaks for fluorescence resonance energy transfer (FRET): one emission as internal standard and the other as FRET donor. Change of ratio of the two emission intensity during the FRET c ...

DESCRIPTIONprovided by applicantThe goal of this Fast Track SBIR is to demonstrate the functionality of PROFUSAandapos s novel injectable tissue oxygen monitors in patients with peripheral arterial diseasePADand to determine the its ability to detect restenosis in critical limb ischemiaCLIPAD is a manifestation of systemic atherosclerosis that affectsmillion people in the U Swith prevalence increa ...