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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. 3-D Thermoacoustic Computed Tomography/Molecular Imaging

    SBC: OPTOSONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop a thermoacoustic computed tomography (TCT) scanner for localizing optical-dye-labeled molecular probes in laboratory mice in vivo. This device offers two significant improvements over fluoresce

    SBIR Phase II 2004 Department of Health and Human Services
  2. A compact dose delivery system for proton radiation therapy

    SBC: PROCURE TREATMENT CENTERS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): In comparison to standard x-ray therapy, proton therapy allows an increased dose of radiation to a tumor and by reducing the amount of radiation to healthy tissue. As a result, it provides the best possible option for using radiation to control and eliminate tumors with the least short and long term toxic side effects. Currently less than 1% of all radiation th ...

    SBIR Phase II 2011 Department of Health and Human Services
  3. A Miniature Non-Contact Rail Temperature Sensor

    SBC: En'urga Inc.            Topic: 081FR2

      This SBIR project will develop a low cost sensor to obtain rail temperatures from a moving train.  The two innovative parts of the proposed sensor are (1) a rugged four wavelength high frequency sensor that accurately measures the natural radiation emitted by the rails, and (2) an advanced algorithm that provides a emissivity compensated temperature from these measurements. The feasibi ...

    SBIR Phase II 2010 Department of Transportation
  4. A national screening test for hearing, administered by telephone.

    SBC: COMMUNICATION DISORDERS TECHNOLOGY, INC            Topic: NIDCD

    DESCRIPTION (provided by applicant): An estimated 36 million US citizens have impaired hearing, but only one in five has had a hearing test. As noted by a recent NIDCD Working Group, In the US there are no readily accessible low-cost hearing screening programs. The authors of this proposal, in collaboration with scientists from Indiana University and VU University Medical Center of Amsterdam, ha ...

    SBIR Phase II 2013 Department of Health and Human Services
  5. A Navigation and Object-Location System to Assist Blind and Low-Vision Individuals in Indoor Environments

    SBC: CREATEABILITY CONCEPTS, INC.            Topic: N/A

    This project demonstrates the technical merit, feasibility, and cost-effectiveness of combining ground-breaking Radio Frequency Identification (RFID) technology with an innovative approach and state of-the-art software to deliver a system capable of removing barriers in vocational settings. This system assists individuals with disabilities to orient themselves and safely navigate in vocational env ...

    SBIR Phase II 2010 Department of Education
  6. A new cancer protein solubility tool: Entropic Bristle

    SBC: Molecular Kinetics Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Expression and purification of cancer-associated proteins are prerequisite steps necessary to study their functions, structures, and interactions. However, these steps are often challenging or even infeasible due to poo r protein solubility. This project seeks to develop a tool, a set of entropic bristle-based AquoProtTM vectors, to dramatically increase the fr ...

    SBIR Phase II 2008 Department of Health and Human Services
  7. A NEW ENZYMATIC TEST FOR THEOPHYLLINE

    SBC: Gds Technology, Inc.            Topic: N/A

    THEOPHYLLINE IS A DRUG CURRENTLY USED BY MOST ASTHMATIC/ALLERGIC ADULTS AND CHILDREN, CONSTITUTING OVER SIX MILLION PATIENTS. THERAPY REQUIRES FREQUENT MONITORING OF THEOPHYLLINE LEVELS IN BLOOD AS IT CAUSES TOXICITY AT CONCENTRATIONS HIGHER THAN 20MG/L AND IS INEFFECTIVE AT LOWER THAN 10 MG/L. CURRENT TESTING IS DONE IN HOSPITAL/COMMERCIAL LABORATORIES AT A COST OF $27.00 PER TEST TO MEDICARE/MED ...

    SBIR Phase II 1991 Department of Health and Human Services
  8. A NEW METHOD FOR THE ANALYSIS OF VITAMIN D

    SBC: NOVILYTIC, LLC            Topic: 100

    DESCRIPTION provided by applicant Most clinical assays begin with blood collection in a laboratory setting The Gates foundation and many others have recognized and attempted to deal with the fact that in much of the world clinical testing is done in a primitive setting The luxury of having a phlebotomist to draw blood with a laboratory to prepare serum or plasma for analysis is not universal ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A new technology for functional solubilization of kinases

    SBC: Molecular Kinetics Inc            Topic: NIGMS

    DESCRIPTION (provided by applicant): Protein kinases are essential enzymes that function primarily as components of signaling pathways, regulating cellular responses such as division, growth, differentiation, and death. Abnormalities in these signaling pathways can lead to wide- ranging and devastating pathological conditions. For these reasons, protein kinases are important targets for drug devel ...

    SBIR Phase II 2011 Department of Health and Human Services
  10. A Noninvasive Sensor/Control Suite for Health Monitoring and Extended Life of Aircraft Generation Systems

    SBC: P C KRAUSE AND ASSOCIATES INC            Topic: N06T007

    Catastrophic failures in aircraft electrical power systems can compromise the readiness, safety, and capabilities of the war-fighter. In this effort, a multi-physics suite of tools will be developed based upon the successful Phase I research to provide a comprehensive prognostics and health management system (PHM) for aircraft generators and associated electrical systems. The PHM will be based upo ...

    STTR Phase II 2008 Department of DefenseNavy

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