Award Data

DESCRIPTION (provided by applicant): The overall goal of the proposed SBIR program is to implement and evaluate a low cost retinal camera, the Laser Scanning Digital Camera (LSDC), in a system for diabetic retinopathy (DR) screening. Untreated DR has reached epidemic levels in underserved populations worldwide. As the LSDC has already demonstrated its readiness for DR screening in preliminary stud ...

DESCRIPTION (provided by applicant): Panic attacks (PA) impact about 23% of adults in community samples. Panic disorder with or without agoraphobia (PDA) tends to be a chronic condition with a lifetime prevalence of 4.7%. When untreated, panic disorder (PD) often leads to debilitating problems, with severe financial and interpersonal costs. Panic Control Treatment (PCT) is an efficacious treatment ...

DESCRIPTION (provided by applicant): Today, arsenic (As) poisoning is one of the major environmental threats worldwide as millions of human beings have been exposed to excessive arsenic through contaminated drinking water. The serious toxicity of arsenic has been well documented. Worldwide, communities demand novel separation technologies for the removal of arsenic from drinking water. Conventiona ...

DESCRIPTION (provided by applicant): Stroke and heart attack are the leading causes of mortality and grave morbidity. The goal of this Fast-Track STTR grant application is to enable preclinical investigation of WE-thrombin, a bioengineered protein C activator enzyme for the treatment of severe, acute thrombotic diseases, in particular ischemic stroke. WE- thrombin is a fundamentally new thrombosi ...

DESCRIPTION (provided by applicant): The ability to conduct basic and applied biomedical research is becoming increasingly dependent on data produced by new and emerging technologies. This data has an unprecedented amount of detail and volume. Researchers are therefore dependent on computing and computational tools to be able to visualize, analyze, model, and interpret these large and complex sets ...

DESCRIPTION (provided by applicant): Heart disease is the leading cause of death in the western societies. The plasma level of high density lipoprotein cholesterol (HDL-C), the good form of cholesterol, is negatively correlated with the risk of heart disease, myocardial infarction, and coronary death. However, current composite risk score tests such as the Framingham tests identify only 1/3rd of i ...

DESCRIPTION (provided by applicant): Education Center for Adoptive Parents Online (ECAPO) Adoption has undergone dramatic change in the past 30 years, due largely to the complexity of contemporary adoptive relationships, which increasingly involve international, multi-ethnic, multi-racial, and foster care placements. Adoptive youth experience consistently high rates of behavior problems and psycho ...

DESCRIPTION (provided by applicant): Feeding problems are a frequent harbinger of nascent neurological damage and are a major obstacle in transitioning infants from hospital nursery to discharge. Severe problems often require repeated hospitalization and tube feeding. Refractory feeding problems contribute significantly to the high cost of health care. Dysfunctional sucking in the newborn, in the ...

DESCRIPTION (provided by applicant): The aim of the project in Phase II is to develop and evaluate a stand-alone, Web-based serious game titled Vstreet-G, and to complete the interactive multimedia instruction on money management by adding a component on investment skills. Emancipation from dependence to living independently is one of the most challenging and feared life events for youth, especial ...

DESCRIPTION (provided by applicant): The overall goal is to develop monoclonal antibody (MoAb)-based compounds capable of blocking human MASP-2 function as potential therapeutic agents for the treatment of age-related macular degeneration (AMD). MASP-2 is a plasma serine protease uniquely required for complement activation via the lectin pathway and may be an attractive target for the development ...