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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SBIR Phase II: Novel Manufacturing Method for Precision Optical Encoders

    SBC: ZS SYSTEMS LLC            Topic: IH

    This Small Business Innovation Research (SBIR) Phase II project aims to develop a novel manufacturing method to produce high-accuracy, optical encoders. Encoders are sensors that measure position, either linear or angular, and convert it into an electronic signal. Modern automation and robotics systems heavily rely on encoders for precision positioning and motion control. The global encoder market ...

    SBIR Phase II 2023 National Science Foundation
  2. STTR Phase II:Stem Cell Delivery in Microscopic Hydrogel Droplets for Faster and More Complete Healing of Equine Tendon and Ligament Injuries

    SBC: CellDrop Inc            Topic: PT

    The broader impact of this Small Business Technology Transfer (STTR) Phase II project involves continued development of technology to extend the therapeutic window of cell-based tissue regeneration therapies. This technology could significantly enhance the scientific understanding of cellular therapies and enable the healing of injuries more rapidly and less invasively than current techniques. A s ...

    STTR Phase II 2023 National Science Foundation
  3. Phosphorus Biofertilizer for Sustainable Agriculture

    SBC: Biomineral Systems LLC            Topic: 812

    Phosphorus Biofertilizer For Sustainable AgricultureProject SummaryOur proposed approach will utilize a novel and patented technology that will solubilize residualinorganic and organic phosphorus in soils as well as make synthetic and organic phosphorusfertilizers available on demand for sustainable crop growth eliminating any leaching losses.TM BioCat-P is a novel next generation biofertilizer bi ...

    SBIR Phase II 2023 Department of Agriculture
  4. Optimization of small molecule SERCA2b activators to inhibit neuron loss in Alzheimer's disease

    SBC: NEURODON, LLC            Topic: NIA

    In this Phase IIB SBIR project for Alzheimer’s disease (AD) drug development, Neurodon LLC proposes to conduct preclinical development and IND-enabling activities on our novel, orally available lead and backup compounds that, in our preceding Phase II project, showed neuroprotection and beneficial effects on learning and memory in a transgenic model of AD. Despite the enormity of AD as a nationa ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. All-in-one Device for Forensic Toxicology Drug Screening

    SBC: WIK DEVICES LLC            Topic: NIDA

    Project Summary/AbstractDrug screening in toxicology cases is performed mainly using immunoassays, gas- chromatography mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS). Immunoassays lack the sensitivity, multiplexing capability, and flexibility to respond to the rise of potent synthetic drugs including fentanyl analogs and synthetic cannabinoids. GC- MS requires exten ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Coccidioides Cytokine Release Assay

    SBC: MIRAVISTA DIAGNOSTICS LLC            Topic: NIAID

    Coccidioidomycosis (CM) is an endemic mycosis caused by the fungi Coccidioides immitis and Coccidioides posadasii, which is native to arid regions of North and South America. It is estimated that up to 350,000 infections occur annually in the U.S. Additionally, up to a third of community acquired pneumonia cases in these areas are thought to be a result of CM. Morbidity associated with CM is subst ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Fluoroscopic drill attachment for orthopedic trauma surgery

    SBC: ECLIPSE ORTHOPAEDICS, LLC            Topic: NIAMS

    Abstract For about 175,000 leg and hip fractures each year, the best treatment is for an orthopaedic surgeon to implant a stiff metal rod, or intramedullary (IM) nail, through the center of the bone and fix the nail to the bone with screws (distal locking). Distal locking can be difficult and time-consuming step and presents two major challenges. First, the procedure uses C-arm fluoroscopy for gui ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. From Academia to Business: Development of Novel Therapeutics Against HPV-Associated Cancer

    SBC: Kovina Therapeutics Inc.            Topic: NCI

    ABSTRACT “High-risk” human papillomavirus (HPV) types such as 16 (HPV-16) are identified in the majority of HPV-associated pre-malignant and malignant pathologies of cervical, anogenital, and oropharyngeal epithelia. TheE6 protein is essential for viral replication. Structure-based computational screening followed by design andsynthesis of derivatives led to the identification of a series of s ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Heat Transfer Correlations for Complete Cryogenic Pool Boiling Curve

    SBC: MUDAWAR THERMAL SYSTEMS INC            Topic: T14

    The proposed effort concerns technologies related to cryogenic propellant production, storage, transfer, and usage to support NASArsquo;s in-situ resource utilization (ISRU) goals. nbsp;They include a broad range of applications, scales, and environments consistent with future NASA missions to the Moon and Mars.nbsp;nbsp;More specifically, the project will addressnbsp;development of a piecewise-sm ...

    STTR Phase II 2023 National Aeronautics and Space Administration
  10. High Temperature, Corrosion, Erosion, and Wear Resistant Coating for Gun Barrels

    SBC: IBC Materials & Technologies, LLC            Topic: AFX234DCSO2

    Gun barrels are exposed to severe conditions in terms of high degree of the corrosion/erosion/thermal shock during firing and currently used traditional coating systems such the hard chromium plating is not able to protect the bore effectively to minimize

    SBIR Phase II 2023 Department of DefenseAir Force
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