Award Data

THIS RESEARCH STUDY DEVELOPS AN INTERACTIVE, MICROCOMPUTER-BASED, ASSISTIVE AND ADAPTIVE DEVICE LOCATOR SYSTEM (ADLS) FOR DISABLED PERSONS. INFORMATION RETRIEVAL IS ORGANIZED AROUND A FUNCTIONAL MODEL OF IMPAIRMENTS AND CORRESPONDING ADAPTIVE DEVICES. THE DESIGN THEORY AND INITIAL DATA BASE CONTENT DRAW UPON EXTENSIVE RESOURCES PREVIOUSLY DEVELOPED FOR PRINT MEDIA DEVICE IDENTIFICATION SYSTEMS. A ...

HEMODIALYSIS IS WIDELY USED TO SUSTAIN LIFE IN INDIVIDUALS WHO HAVE LOST KIDNEY FUNCTION. THE MEMBRANE MATERIAL MOST COMMONLY USED FOR THIS PURPOSE IS REGENERATED CELLULOSE. HOWEVER, REGENERATED CELLULOSE IS NOT INERT; IT STIMULATES THE COAGULATION AND COMPLEMENT SYSTEMS AND MAY BE A CAUSE OFBOTH ACUTE AND CHRONIC MORBIDITY FOR THE PATIENT. FURTHER, ITS PHYSICAL PROPERTIES LIMIT METHODS OF STERILI ...

PERITONEAL DIALYSATE USED IN TREATING PATIENTS WITH END- STAGE RENAL DISEASE UTILIZES THE OSMOTIC FORCE OF HIGH CONCENTRATIONS OF GLUCOSE TO TRANSFER WATER FROM THE BODY POOL TO THE DIALYSATE. THIS PROCEDURE HAS BEEN IDENTIFIED AS A SOURCE OF SEVERAL METABOLIC PROBLEMS IN SUCH PATIENTS, ESPECIALLY THOSE WHO ARE ALSO DIABETIC. UNIVERSITY MEDICAL ASSOCIATES WILL DEVELOP A MIXTURE OF CHARGED PEPTIDES ...

ISR PROPOSES TO CONDUCT A PROOF-OF-CONCEPT STUDY OF A UNIQUE HIGHFLUX TWO-PHASE THERMAL MANAGEMENT SYSTEM FOR SPACECRAFT. THIS SYSTEM COUPLES HIGH POWER DENSITY EVAPORATIVE SPRAY COOLING WITH AN EXPANDABLE VAPOR STORAGE AND CONDENSATION DEVICE. PREVIOUS WORK HAS DEMONSTRATED THE IMMENSE POTENTIAL OF EVAPORATIVE SPRAY COOLING FOR REMOVING EXTREMELY HIGH HEAT FLUXES (@0 W/CM[2]) WITH VERY SMALL TEMP ...

THIS RESEARCH STUDY DEVELOPS AN INTERACTIVE, MICROCOMPUTER-BASED, PICTURE ICON LAYOUT AND AUTHORING SYSTEM FOR EDUCATORS, COMMUNICATIONS SPECIALISTS, AND EDUCATIONAL TECHNOLOGISTS WHO ADAPT OR FABRICATE COMMUNICATIONS AIDS AND SYSTEMS FOR NON-VOCAL OR SPEECH-IMPAIRED CHILDREN OR ADULTS. A PROTOTYPE PICTURE ICON LAYOUT SOFTWARE (PILS) SYSTEM WILL BE DESIGNED FOR THE UNICORN II EXPANDED KEYBOARD (UN ...

IN SOME PATIENTS, PHOSPHOLIPID-BINDING ANTIBODIES HAVE BEEN ASSOCIATED WITH RECURRENT VENOUS AND/OR ARTERIAL THROMBOSIS AS WELL AS WITH RECURRENT FETAL LOSS (THE ANTIPHOSPHOLIPID SYNDROME, OR APS). THESE ANTIBODIES ARE INDUCED IN A VARIETY OF CLINICAL CIRCUMSTANCES, AND IT IS LIKELY THAT THE ABOVE CLINICAL ASSOCIATIONS ARE LIMITED ONLYTO PATIENTS WITH PARTICULAR SUBGROUPS OF ANTIPHOSPHOLIPID (APL) ...

THIS PROJECT DEVELOPS AND FIELD TESTS A PROTOTYPE SOFTWARE/HARDWARE ASSESSMENT PACKAGE TO SUPPORT ASSISTIVE TECHNOLOGY ASSESSMENT PERSONNEL RESPONSIBLE FOR SELECTION OF APPROPRIATE CONTROL INTERFACE DEVICES FOR PERSONS WHO HAVE DIFFICULTY INTERACTING WITH THEIR ENVIRONMENT. THIS POPULATION INCLUDES INDIVIDUALS WITH LEARNING, INTELLECTUAL, OR PHYSICAL DISABILITIES; VERY YOUNG PERSONS; AND/OR ELDERL ...

OLDER ADULTS HAVE MORE TRAFFIC CONVICTIONS AND ACCIDENTS AND INCUR MORE FATALITIES PER MILE DRIVEN THAN ANY OTHER AGE GROUP. THE AIM OF THE RESEARCH IS TWO-FOLD: 1) TO TAKE THE RESEARCH PARADIGMS DEMONSTRATED TO BE RELATED TO A VARIETY OF EVERYDAY FUNCTIONAL VISION PROBLEMS IN OLDER ADULTS AND EMBODY THEM IN A SCREENING/TRAINING DEVICE WHICH CAN BE USED BY PHYSICIANS AND EYE-CARE SPECIALISTS IN DI ...

THIS PROJECT DEVELOPS AND FIELDTESTS A COMMERCIAL PROTOTYPE SOFTWARE PACKAGE DESIGNED TO PROVIDE USERS OF SINGLE-SWITCH INPUT DEVICES CONTROL ACCESS TO EDUCATIONAL SOFTWARE, MULTIMEDIA PROGRAMS, AND RECREATIONAL ACTIVITIES FOR IBM AND PC-COMPATIBLE COMPUTERS. THIS POPULATION INCLUDES INDIVIDUALS WITH LEARNING, INTELLECTUAL, OR PHYSICAL DISABILITIES; VERY YOUNG PERSONS; OR ADULTS WHO ARE ELDERLY O ...

STUDIES BY THE APPLICANT ON THE METABOLISM AND PHARMACOLOGY OF ADD17014, A NOVEL TRIAZOLINE ANTICONVULSANT, HAVE LED TO THE DISCOVERY OF THE AMINOAKYLHETEROCYCLES AS A UNIQUE CLASS OF ANTICONVULSANT AGENTS. INITIAL WORK ON AMINOALKYLPYRIDINES INDICATE THEY ARE NONTOXIC, AND HIGHLY EFFECTIVE BY THE ORAL ROUTE, WITH PROTECTIVE INDICES GREATER THAN 20. THEY IMPAIR PRESYNAPTIC RELEASE OF L-GLUTAMATE A ...