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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. NECTAR: The Negative CO2 Emission Transition Roadmap

    SBC: CARBON SOLUTIONS LLC            Topic: C5322c

    C53-22c-271119Meeting climate-stabilizing energy transition goals requires using hybrid-energy CO2 capture systems like Direct Air Capture (DAC) to remove billions of tonnes of CO2 from the atmosphere. Deploying this capacity will be difficult because it is complex and energy intensive infrastructure, and there must also be buy- in from communities living in locations best suited for it. The chall ...

    SBIR Phase II 2023 Department of Energy
  2. SBIR Phase II:Modular And Reconfigurable Electromagnetic Navigation System For Surgical Interventions And Medical Robotics

    SBC: Radwave Technologies Inc.            Topic: R

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is a novel electromagnetic navigation system offering a transformative solution for a wide range of medical procedures that demand accuracy, efficiency, and safety. The result of this capability and its subsequent commercialization will positively affect the outcomes of medical procedures for ...

    SBIR Phase II 2023 National Science Foundation
  3. SBIR Phase II:Predictive Tools for Characterizing Carbon Sequestration in Mined Materials

    SBC: Tamara Diedrich            Topic: ET

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to fully realize the potential for weathering of mine waste to remove carbon dioxide (CO2) from the atmosphere. By helping mining companies in this effort, this project will positively impact human health and welfare while potentially producing a competitive advantage to the domestic minin ...

    SBIR Phase II 2023 National Science Foundation
  4. SBIR Phase II: A robust production scheduling optimizer for aerospace manufacturers

    SBC: Vivek Saxena            Topic: M

    The broader impact of this Small Business Innovation Research (SBIR) Phase II project seeks to increase the competitiveness of the US in manufacturing high value parts for shops with high product variety, low volumes, large lead times, and large set up times.The application addresses a need to find the optimal way of utilizing existing resources in order to maximize production rates. The proposed ...

    SBIR Phase II 2023 National Science Foundation
  5. SBIR Phase II:Clinical scale and testing of the first virus-free precision gene edited cell therapy for veterinary oncology

    SBC: LifEngine Animal Health Laboratories Incorporated            Topic: BM

    The broader impact of this Small Business Innovation Research (SBIR) Phase II project is the development of a commercially-ready cell engineering platform that will enable a curative therapy for cancer in the veterinary market.An estimated 250,000 dogs get B cell lymphoma every year. Chimeric Antigen Receptor (CAR)-T cell therapy offers hope for a treatment for this disease. The project platform f ...

    SBIR Phase II 2023 National Science Foundation
  6. Microbial Synthesis of Therapeutic Bile Acids for Alzheimer's Disease

    SBC: Metselex, Incorporated            Topic: 105

    ABSTRACT This Phase STTR Phase II proposal aims to engineer and scale-up a synthetic metabolic pathway in a microbial host to produce UDCA and related compounds. Additionally, the UDCA produced from the engineered synthetic metabolic pathway will be used to synthesize derivatives for testing in our Alzheimer’s Disease cell and animal models. The proposed work has high intellectual merit for the ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Post-surgical Incision Management Device to Prevent Ostomy Complications

    SBC: FISTULA SOLUTION CORPORATION            Topic: 102

    Project Summary/Abstract Over 100,000 patients of all ages undergo ostomy surgery in the United States (US) annually due to a variety of pathophysiologic conditions including colorectal cancer, inflammatory bowel disease (Crohn’s disease and ulcerative colitis), bowel obstruction, diverticulitis, and many other medical conditions. Ostomy surgery may also be necessary in cases of severe abdominal ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  8. Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in at-risk Older Adults

    SBC: MOAI TECHNOLOGIES, LLC            Topic: NIA

    Project Summary/Abstract Alzheimer’s disease (AD) affects more than six million Americans currently and is projected to affect 14 million at a cost of $1.2 trillion in 2050. Despite its tremendous impacts and the limited influence of pharmacological therapies, attention has been brought to non-pharmacological interventions as promising therapeutic strategies for the prevention of cognitive decli ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Development of novel therapeutics for cancer cachexia

    SBC: EMMYON, INC.            Topic: NCI

    PROJECT SUMMARY / ABSTRACT Cancer-induced skeletal muscle atrophy is a central and defining feature of the cancer cachexia syndrome, a highly prevalent condition that affects over 50% of patients with advanced cancer and over 500,000 patients per year in the U.S. In addition to being highly prevalent, cancer-induced skeletal muscle atrophy has devastating consequences for patients; it reduces phys ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Treating non-small cell lung tumors with a novel inhaled dry powder chemotherapeutic formulation

    SBC: Quench Medical Inc.            Topic: 102

    Project Summary / Abstract Significance Lung cancer is the leading cause of cancer mortality with a 5-year survival rate of less than 20% following standard of care therapy. Problem Despite the use of aggressive surgery, combination chemotherapy and immunotherapy, a major limitation in the control of primary and metastatic non-small cell pulmonary tumors with the use of the systemic administration ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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