Award Data

Space missions are immensely costly endeavor – fault free function of the hardware and software used therein are highly critical to mission success. Being highly complex, manual intervention in operation, troubleshooting, and health management related areas are labor intensive and time consuming. On top of that with time the complexities of the systems are increasing, and the performance and avai ...

Optoelectronic integrated circuits offer radiation-hard solutions for satellite systems with much improved SWPB (size, weight, power and bandwidth). The phased array for sensing and data transfer is one system that optoelectronics can impact in the near term. It is known that optical delay could enable optimum beam steering electronic scanning . Lidar is another sensing system using optical beams ...

Proton Exchange Membrane (PEM) water electrolyzers have undergone continuous development for the generation of oxygen and hydrogen for commercial, military and space applications since the 1970's. Unfortunately, conventional technology developed over this time period has required a complex balance of plant that adds to the overall weight of the system package. Research in the past two decades resu ...

Hydrogen is an essential resource for space missions. NASA has a need for equipment to generate, handle and store hydrogen. In terms of handling hydrogen, conventional rotating mechanical pumps and compressors require extensive modification and have limited reliability. Electrochemical pumping and compression of hydrogen occurs without any moving parts and is highly reliable and efficient. Sustain ...

A Probabilistic Fatigue Damage Assessment Network (PFDAN) toolkit for Abaqus will be developed for probabilistic life management of a laminated composite structure with both microcracking induced stiffness degradation and cyclic loading induced delamination crack growth without remeshing. It is based on a high fidelity Fatigue Damage Assessment Network (FDAN) which includes 1) a coupled continuum ...

DESCRIPTION (provided by applicant): The long-term product goal of this project is a small molecule therapeutic to treat rheumatoid arthritis (RA), which acts by reducing the inflammatory response triggered by the pro-inflammatory cytokine macrophage migration inhibitory factor (MIF). Since MIF is an upstream regulator of the inflammatory cascade, small molecule therapeutics targeting MIF activity ...

DESCRIPTION (provided by applicant): We propose to develop a software package to automatically evaluate a subject's beta amyloid PET scan (using either C11-PIB, F18-florbetaben, or F18-florbetapir, F18-flutemetamol) by normalizing the subject's scan, masking away non-gray matter tissue (without relying on co-registered MRI scans), placing standardized ROIs onto the transverse slices, and ...

This Small Business Innovation Research (SBIR) Phase II project investigates the viability of an electrochemical device for separation and compression of hydrogen from low-pressure mixed gas streams that are critical for industrial gas and energy applications. Previous studies have shown that hydrogen derived from reformation of hydrocarbons produces a gas stream rich in CO2, CO and H2. It has bee ...

This Small Business Innovation Research (SBIR) Phase II project aims to develop a wireless, needle implantable miniaturized (0.5 x 0.5 x 5 mm) sensor for continuous glucose monitoring, with provisions for internal self-calibration that ultimately eliminates the need for frequent, external finger-pricking. As part of Phase I project, the internal calibration routine has been developed and its ?proo ...

This Small Business Innovation Research Phase II project addresses current limitations in hydrogen compression and enables reduction in hydrogen requirements for several applications through recycling of exhaust hydrogen containing water and other benign impurities. In Phase 1, feasibility of operating a proton exchange membrane (PEM)-based device as a high efficiency electrochemical compressor/pu ...