Award Data

C53-33c-271423Active pixel sensors have been developed and implemented in a wide array of applications, including image sensors for cameras, sensors for medical imaging, and as detectors for nuclear physics investigations with the Relativistic Heavy Ion Collider and the Large Hadron Collider. Many of these applications, including nuclear physics detectors, medical imaging sensors, and sensors for ...

This SBIR Phase I project will develop a machine learning-assisted family math preparation program that will help and encourage parents to provide early math instruction to young children, ages 4-8. Along with reading, developing mathematical proficiency is arguably one of the most important skills for young children to acquire, particularly with the growing importance of STEM (science, technology ...

Kultevat Inc. aims to produce natural rubber from Taraxacum kok-saghyz (TKS) at scale toachieve high quality product at a price point that is attractive to customers in particular to US basedcompanies. To date the economics of growing TKS and extracting rubber from its roots at a pricepoint that is competitive with Hevea rubber has not been demonstrated. During Phase I research anRNAi gene silenci ...

Age-related hearing loss (ARHL) is the predominant neurodegenerative disease of aging. Recent animal studies have demonstrated that the earliest cochlear pathology due to noise and aging involves a loss of the inner hair cell ribbon synapse. The early consequences of this synaptic loss are not believed to affect hearing sensitivity, but rather, impair speech understanding in background noise. Whil ...

PROJECT SUMMARY Sarya LLC (Sarya) is a nuclear medicine technology company formed to commercialize radiopharmaceuticals. The goal of this Fast-Track STTR is to develop a new specific imaging agent for diagnosis, staging, and treatment of the hematological cancer, multiple myeloma (MM). MM is the 2nd most common blood cancer with an estimated 32,000 new cases and 13,000 deaths per year. Accurate de ...

Acute ischemic stroke (AIS) results from a blood clot in the neurovasculature and is a leading cause of death and neurological disability in the United States (US). AIS impacts more than 700,000 Americans annually, with a 65% chance of death or severe disability. By 2030, it is expected that the AIS economic burden will exceed $180B in the US alone.Standard AIS therapies include FDA-approved throm ...

Project Abstract/SummaryMotion related artifacts are a significant source of cost to the healthcare system. With over 12,000 MRI scanners in the U.S. and estimates that $434,000 are lost per scanner each year, motion in MRIs is costing our health care system approximately $4B yearly. Our FDA-cleared software solution Framewise Integrated Real- Time MRI Monitoring (FIRMM) mitigates data lost due to ...

PROJECT SUMMARY Streptococcus agalactiae, commonly referred to as Group B Streptococcus (GBS), is a leading cause of neonatal meningitis and sepsis worldwide. GBS neonatal disease manifests as early onset invasive disease, defined as disease between birth and 6 days of life, or late onset invasive disease, defined as disease occurring between 7 and 89 days. In some instances, early onset disease i ...

Abstract: Immunophotonics is a biotech company developing a synthetic biopolymer, IP-001, to potentiate a systemic immunotherapy via microwave (MWA) thermal tumor ablation for treatment of Hepatocellular carcinoma (HCC). The goal of this SBIR Fast Track is to complete preclinical safety and efficacy testing to support an investigational new drug (IND) application based on the feedback from a meeti ...

Our innovation, Focused LIBS for Elements in Water IDentification (FLEW.ID), is a compact, cost-effective, and sensitive instrument for monitoring the elemental composition of aqueous solutions in plant growth systems on-board the International Space Station (ISS). FLEW.ID utilizes a miniaturized, low-pulse energy laser for performing laser-induced breakdown spectroscopy (LIBS) measurements that, ...