Award Data

C53-21a-271193Assuring trouble-free performance of downhole and surface components is critical for generation of low- cost electricity from geothermal energy systems. Because geothermal environments can be extremely corrosive, managing the corrosion of alloys used in geothermal system through a combination of proper alloy selection and operational practices is essential. Unfortunately, materials s ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is advancement in the development of an effective wound closure product for internal gastrointestinal (GI) surgical applications. Anastomotic leaks resulting from ineffective GI surgical wound closures are associated with significant healthcare and economic costs. Effective closure of wounds ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to enhance American and global healthcare through new technologies enabling clinical translation of gene therapies. One of the major unmet needs within biotechnology is a delivery technology that enables gene therapies to reach the desired organ within the body without raising an immu ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to potentially improve the quality of life for individuals suffering arm and hand impairments from stroke, through a medical device for telerehabilitation. Each year, ~800,000 people have a stroke in the United States, and about 65% of them suffer long-term upper extremity impairments. Due ...

The broader impact of this Small Business Technology Transfer (STTR) Phase II project is the development of an electrocatalytic formic acid production process directly from carbon dioxide (CO2) and electricity. This process will mitigate greenhouse gas emissions while producing formic acid, currently used in agriculture for silage preservation, leather tanning, and the chemical industry. The econo ...

The use of coal waste and biomass has significant environmental benefits, and it can contribute to promoting a low-carbon economy via hydrogen production. These feedstocks can be cost effective, are readily available, and in the case of biomass are renewable with the near elimination of greenhouse gases. But there are issues with gasifying waste coal and biomass. The first one is the widely varyin ...

The use of high throughput genetic data has transformed animal agriculture dramatically overthe last 17 years.Large breed associations and national breeding programs are collecting genomewide genotypes and implementing genomic selection to improve production phenotypes.Thesetechnologies have proven both powerful and transformative.They have also become inexpensive.Whole genome genotypes can be gen ...

ABSTRACT Approximately 700,000 people in the United States are diagnosed with a primary brain tumor. Of these, malignant gliomas (MGs) account for approximately 40% of all intracranial tumors, with an overall survival rate of only ~34%. Surgical resection remains the cornerstone of therapy and the extent of resection correlates with survival. Fluorescence imaging has emerged as an adjunctive techn ...

Project Summary I-RED Southeast XLerator Network, powered by XLerateHealth, LLC in collaboration with the University of Kentucky as the lead academic partner institution, proposes to develop a suite of experience-based entrepreneurship education products and commercialization education tools to address the needs of academic institutions and their faculty, researchers, innovators, and graduate/unde ...

7. Project Summary/AbstractC. difficile now causes more hospital-onset infections and deaths in the US than any other pathogen and is the most important cause of healthcare-associated diarrhea among adults in industrialized countries. In 2017, there were an estimated 462,100 combined healthcare- and community-associated C. difficile infection cases in the US, and 20,500 in-hospital deaths. In a ra ...