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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Adaptive Clinical Efficacy Evaluation of ONC201 in Recurrent High Grade Glioma

    SBC: Oncoceutics, Inc.            Topic: 102

    Project Summary We propose a two arm adaptive Phase II clinical trial to evaluate ONCa selective antagonist of the G protein coupled receptorGPCRdopamine receptor domainDRDin recurrent glioblastomaGBMand diffuse midline glioma associated with very poor prognoses and limited treatment optionsDRDis overexpressed in high grade gliomas and controls Akt ERK signaling pathwaysDownstream of target engage ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. Response Surface Modeling of Aerodynamic Interference Effects for Refueling Scenarios

    SBC: COMBUSTION RESEARCH AND FLOW TECHNOLOGY INC            Topic: N161003

    Aerial refueling is a mission-critical component of Navy operations. Refueling is made difficult by the interference between the tanker and receiver aircraft. The receiver aircraft may experience various forms of disturbances during approach, stressing the skills of a pilot or the control system of an autonomous vehicle. Current flight simulation capabilities are unable to reproduce the impact of ...

    SBIR Phase II 2018 Department of DefenseNavy
  3. Guided Missile Submarine SSGN Seawater System Antifouling

    SBC: Interphase Materials, Inc.            Topic: N161041

    In this Phase II contract, Interphase Materials will further validate the efficacy of its antibiofouling surface treatment (AST) in preventing biofouling on OHIO-class submarine seawater cooled heat exchangers (HX). The AST is a molecularly thin surface treatment that binds to the substrate, protecting the surface from organism attachment. An intensive field study will be conducted, incorporating ...

    SBIR Phase II 2018 Department of DefenseNavy
  4. Hybrid Acoustic Emission and Guided Wave Inspection System for Radar Tower Structures

    SBC: Fbs, Inc.            Topic: AF161011

    A novel hybrid acoustic emission (AE) and guided wave (GW) inspection approach for radar towers inspection is presented. Keeping aging radar sites (many are over 50 years old) in good repair is important because they are critical intelligence components that provide advanced aircraft notification. This proposed work will continue development of new, patent-pending shear-type AE sensors, and apply ...

    SBIR Phase II 2018 Department of DefenseAir Force
  5. Nonlinear Ultrasonic Guided Wave System for Detection of SCC

    SBC: Fbs, Inc.            Topic: AF161017

    Sudden structural failure caused by stress corrosion cracking (SCC) in aircraft components is becoming a severe safety threat to Air Force aircraft and other aviation vehicles. Detection of SCC often occurs late in the damage development cycle, in which fast-growing macroscale cracking has already developed. This significantly increases depot maintenance cost and can negatively impact aircraft ava ...

    SBIR Phase II 2018 Department of DefenseAir Force
  6. Secure Wireless Disposable Pulse Oximeter Patch that Generates a PPG Waveform

    SBC: Stancil Technologies, LLC            Topic: A16053

    Stancil Technologies is developing WiSPR (Wearable Physiological Monitoring with Low-Power Wireless Sensing, Processing and Recording), a disposable multi-sensor patch capable of collecting and wirelessly transmitting a variety of physiological measurements to a handheld smartphone or tablet. WiSPR can be quickly applied by a combat medic or soldier to provide real-time health status monitoring us ...

    SBIR Phase II 2018 Department of DefenseArmy
  7. Interlocking Gecko-Inspired Microfiber/Microridge Interfaces for Flexible, High Pressure Resistant Chem Bio Closure Systems

    SBC: nanoGriptech, Inc.            Topic: A16062

    The threat posed by Chemical Warfare Agents remains one of the key concerns in the defense against catastrophic attacks, underscoring the need to have equipment which prevents exposure to Chem/Bio (CB) agents. Conventional fastening options for such equipment generally consist of zippers, hook and loop closures, or zip-track systems, all of which have drawbacks that make them susceptible to permea ...

    SBIR Phase II 2018 Department of DefenseArmy
  8. Efficient Prediction of Thermal Stresses and Distortion in Complex Optimized Missile Structures

    SBC: Materials Sciences LLC            Topic: A16104

    Additive manufacturing (AM) technology offers the potential to fabricate complex geometries that cannot be realized using conventional subtractive methods.In current industrial AM processes, determination of the type and distribution of support structure is often based solely on technician experience.This process is far from optimal and as a result, significant non-recurring engineering costs are ...

    SBIR Phase II 2018 Department of DefenseArmy
  9. High Performance Actuators for Solid Propulsion Control Systems

    SBC: Solid State Ceramics, Inc.            Topic: MDA16010

    Phase II will exit with a new and substantially test-rig validated new solid-state integrated propulsion control valve actuator design for Divert and Attitude Control Systems (DACS) that present a unique engineering challenge in that they need to fit in tight volumes, require very high performance and are subject to extreme temperatures that fills the void of providing a highly engineered but simp ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency
  10. Development of Lyocell-Based High Temperature Composites for Structural Insulator Applications

    SBC: MATERIALS RESEARCH & DESIGN INC            Topic: MDA16020

    Materials Research & Design, Inc. submits this Phase II SBIR proposal to address Rayon Replacement for High Temperature Materials. The proposed program seek to demonstrate repeatable processability of low conductivity, low modulus, high strength, Lyocell-Based materials that can provide sustained, domestic replacement for rayon based structural insulators. MR&D will manage the program and perform ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency

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