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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accelerated BAC Library Construction And Analysis

    SBC: LUCIGEN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Large insert DMA libraries are essential resources for the molecular analysis of the human genome and other genomes important to our well-being. The identification of susceptibility genes for complex disorders is critically dependent on a complete and accurate sequence assembly. Comparative genomics reveals new information about metabolic pathways, cancer, hor ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Accelerated Development of High-Performance Mo-Si-B-X Alloys via an Approach of Integrating Thermodynamic Modeling with Experimental Study

    SBC: Computherm, LLC            Topic: AF07T003

    The proposed study aims at accelerated development of Mo-Si-B-X (X=Ti, Zr, Hf, Re, Mn) alloys with an optimized balance of properties, via an approach of integrating thermodynamic modeling with experimental study.   On the basis of the Mo-Si-B-X (X=Ti, Zr, Hf) database developed in Phase I, a thermodynamic database of the Mo-Si-B-O-X (X=Ti, Zr, Hf, Re, Mn) system will be developed using the Calp ...

    STTR Phase II 2009 Department of DefenseAir Force
  3. Accelerating Functional Maturation of Human Neurons for High-Throughput Screening

    SBC: BrainXell, Inc            Topic: 44

    Project Summary/AbstractNeurological and psychiatric disorders, including drug abuse and addiction, exert a devastating personal and economic toll on patients, families, caregivers, and society. This is in part due to our failure in developing effective medications, which in turn is due to the use of drug discovery platforms that are often not relevant to target diseases. The recent development of ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Access Language Arts

    SBC: ATTAINMENT CO., INC.            Topic: N/A

    Purpose: Instruction in English Language Arts (ELA) for students with severe intellectual disabilities and autism can be challenging, as these students often do not have the skills to engage with text. In recent years, special education experts have proposed a comprehensive approach to supporting students with intellectual disabilities and autism in ELA, centered on strategies including word ident ...

    SBIR Phase II 2014 Department of Education
  5. Accurate accessible cloud software for protein folding for molecular biologists

    SBC: DNASTAR, INC.            Topic: 100

    DESCRIPTION provided by applicant Most drugs interact with protein molecules to elicit a cellular response Traditional drug discovery is a laborious and expensive experimental process so computational approaches to assess protein function and to accelerate the discovery process are in high demand Virtual drug screening and structure based drug design represent computational approaches that c ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Accurate protein folding software to predict ligand induced conformational changes in G protein coupled receptors

    SBC: DNASTAR, INC.            Topic: 100

    Abstract In humans and animals G protein coupled receptors GPCRs are embedded on cell surfaces and function as key regulators of physiological events by transmitting signals from extracellular stimulants across the cell membrane into the cell Impaired or abnormal GPCR function can result in disordered physiological processes causing a broad and diverse range of diseases For this reason GPCRs ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A Clinical Trial of Antimicrobial Skin Substitutes for Treatment of Diabetic Ulce

    SBC: Stratatech Corporation            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this Type 2 Competitive Renewal SBIR application to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to conduct a phase I/II clinical trial to investigate the safety and earlyefficacy of a novel antimicrobial living human skin substitute for the treatment of a life-threatening complication of diabetes: chronic, nonhea ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  8. A COMPUTER SYSTEM FOR THE MOLECULAR BIOLOGY LABORATORY

    SBC: DNASTAR, INC.            Topic: N/A

    THE DEVELOPMENT OF RAPID SIMPLE METHODS FOR SEQUENCING DNA HAS LED TO A REQUIREMENT FOR THE DAY TO DAY USE OF COMPUTERSIN THE MOLECULAR BIOLOGY LABORATORY. THE LOW COST OF MICROCOMPUTERS HAS GENERATED CONSIDERABLE INTEREST IN THESE SMALL MACHINES AS THE MOST COST-EFFECTIVE WAY TO MEET THIS REQUIREMENT. THE PURPOSE OF THE FEASIBILITY STUDY PROPOSED HERE IS TO DEFINE THE HARDWARE AND SOFTWARE REQUIR ...

    SBIR Phase II 1984 Department of Health and Human Services
  9. Additively-Manufactured Insulated Propulsion Components (AMIPC)

    SBC: Exo-Atmospheric Technologies LLC            Topic: MDA21T005

    In Phase II, Exo-Atmospheric Technologies, LLC (EXO) will team up with multiple propulsion providers to fabricate throat inserts, pintles, and other structural components to verify and validate their Additively-Manufactured Insulating Propulsion Component (AMIPC) technology. EXO will use analysis tools to create components optimized for thermal insulation and structural performance utilizing multi ...

    SBIR Phase II 2023 Department of DefenseMissile Defense Agency
  10. Additive Manufacturing of Large, Complex 3D, Metal and Alloy Structures for High-Vacuum Applications

    SBC: XANTHO TECHNOLOGIES LLC            Topic: C4824a

    Fusion science has immediate need for fabrication of high-vacuum complex 3D structures. We propose to develop the know-how necessary to use metal additive manufacturing (AM) to produce structures (such as chambers) possessing vacuum and structural characteristics that meet this need. Traditional methods for producing high-vacuum components typically require the manufacturing of multiple parts, sub ...

    SBIR Phase II 2022 Department of Energy
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