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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. HIGH THROUGHPUT ASSAYS FOR DRUG GLUCURONIDATION

    SBC: Bellbrook Labs, LLC            Topic: N/A

    Drug metabolism problems such as production of toxic metabolites and unfavorable pharmacokinetics cause almost half of all drug candidate failures during clinical trials. Although glucuronidation is one of the most important routes of drug metabolism, the broad and overlapping substrate specificity of the hepatic UDP-glucuronosyltransferases (UGTs) that catalyze glucuronidation remains poorly unde ...

    SBIR Phase II 2002 Department of Health and Human Services
  2. Novel Cost-Effective Production of High Quality Papers

    SBC: BIOPULPING INTERNATIONAL, INC.            Topic: N/A

    The overall goal of the proposed program is to demonstrate the technical and scientific feasibility of combining the biopulping and fiber loading technologies at a pilot-scale simulating industrial conditions to minimize the initial research and development costs. The combined technology will save electrical energy, improve paper quality (strength and optical properties), and reduce the environmen ...

    SBIR Phase II 2002 Department of Agriculture
  3. AN EXPANDED GENETIC INFORMATION SYSTEM

    SBC: ERAGEN BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The DNA alphabet is not limited to the four standard nucleotides. Rather, twelve nucleobases forming six base pairs joined by mutually exclusive hydrogen bonding patterns are possible within the geometry of the Watson-Crick base pair. These form An Expanded Genetic Information System (Aegis), a new, "rule based" molecular recognition system that carries protein ...

    STTR Phase II 2002 Department of Health and Human Services
  4. FACILITATING DEMENTIA SCREENING, EDUCATION AND REFERRAL

    SBC: HEALTHCARE TECHNOLOGY SYSTEMS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This application proposes to develop two interactive voice response (IVR) products: Alzheimer's Early Recognition Telephone System (ALERTS) and Telephonic Remote Evaluation of Neuropsychological Deficits (TREND). Research results from a previous Phase I grant provide the conceptual and scientific foundations for these products. Two independent research projec ...

    SBIR Phase II 2002 Department of Health and Human Services
  5. SBIR/STTR Phase II: Three-Dimensional Atom Probe Imaging for Nano-Biotechnology

    SBC: Imago Scientific Instruments            Topic: N/A

    This Small Business Innovation Research Phase II project will develop the Local Electrode Atom Probe (LEAP) to rapidly provide three-dimensional atomic-scale imaging and elemental identification of nano-biotechnology devices. Structural characterization of nano-biotechnology devices is currently problematic because available microscopy and analytical techniques have substantial limitations in quan ...

    SBIR Phase II 2002 National Science Foundation
  6. SBIR Phase II: A New Digital Video Surveillance System

    SBC: JunTech, Inc.            Topic: N/A

    This Small Business Innovation Research (SBIR) Phase II project will develop a digital video surveillance system prototype. Over the past few years, video surveillance systems have been moving from analog to digital. The success of a digital video surveillance system depends on three key enabling technologies: compression, search and retrieval and network transmission. Existing commercial systems ...

    SBIR Phase II 2002 National Science Foundation
  7. SBIR/STTR Phase II: Thermostable Phage DNA Polymerases: Improved Tools for Genomics Research

    SBC: LUCIGEN CORPORATION            Topic: N/A

    This Small Business Innovation Research Phase II project will develop novel DNA polymerase reagents for use in current and developing DNA diagnostic procedures. The approach is to develop thermophilic phage DNA replicases in place of the currently used DNA repair enzymes. The feasibility of this approach was demonstrated during Phase I research. This follow on Phase II project will extend the meth ...

    SBIR Phase II 2002 National Science Foundation
  8. NOVEL VIRUS-LIKE PARTICLES FOR NUCLEAR DNA DELIVERY

    SBC: MIRUS BIO CORPORATION            Topic: N/A

    An emerging hybrid between the classical viral and non-viral gene delivery fields: synthetic virus-like vectors have gained ground. These condensed DNA particles carry one or more virus-like characteristics that make them more efficient at (a) certain step(s) of delivery, yet maintaining advantages over real viruses. The first goal of these studies is to lay the foundation for the construction of ...

    SBIR Phase II 2002 Department of Health and Human Services
  9. Mixing and Combustion of Gelled Propellants

    SBC: Orbital Technologies Corporation            Topic: N/A

    ORBITEC proposes to continue to empirically develop and analytically model the mixing and combustion of gel propellants in the rocket combustion chamber flow field generated by innovative vortex injection schemes. The gels are injected circumferentiallytangent to the chamber wall. Streaming the propellants on the wall provides required shear to keep the non-Newtonian fluids liquefied to allow mix ...

    SBIR Phase II 2002 Department of DefenseArmy
  10. Virtual Collaborative Training and Operations Simulation System

    SBC: Orbital Technologies Corporation            Topic: N/A

    The goal of VCTOSS is to enable the creation and deployment of highly effective training and operations support materials by using new lightweight 3D simulation technology. This lightweight approach to 3D simulation makes it possible to: (1) electronically transmit materials to physically distributed mission participants, (2) run 3D simulations on COTS portable computers used on-orbit, and (3) eco ...

    SBIR Phase II 2002 National Aeronautics and Space Administration

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