Award Data

THE PROJECT WILL DEVELOP A NOVEL MINIATURE PULSE WIDTH MODULATED POWER DRIVER FOR ACTUATORS, I.E. DC MOTOR. THE POWER DRIVER WILL DELIVER 50 AT 50VDO IN A DOUBLE INON PACKAGE. THIS COMPACT DESIGN CAN ONLY BE ACHIEVED THROUGH THE INNOVATIVE COMBINATION OF MODER POWER SEMICONDUCTOR TECHNOLOGIES, PROPRIETORY CIRCUIT DESIGN, AND STATE-OF-THE-ART PACKAGING TECHNOLOGY WHICH UTILIZES NEW HEAT CONDUCTIVE ...

APPLICATION OF BIOTECHNOLOGY TO THE PRODUCTION OF 4-HYDROXYBENZOCYCLOBUTENE WILL ALLOW BULK MANUFACTURE OF THIS POLYMER PRECURSOR BY MORE ECONOMICAL MEANS THAN IS CURRENTLY AVAILABLE. DEVELOPMENT OF SUCH A PROCESS WOULD ALLOW INDUSTRIAL APPLICATIONS OF BCB-BASED POLYMER MATERIALS.

BECAUSE BACTERIAL DISEASES ARE FREQUENTLY TRANSMITTED THROUGH CONTAMINATED WATER, THE DETECTION OF MICROBIOLOGICALCONTAMINATION IS IMPORTANT, TO ENSURE SANITARY WATER SUPPLIES. CURRENT TESTS ARE LABOR INTENSIVE AND TAKE SEVERAL DAYS TO CONFIRM CONTAMINATION LEVELS. THIS PROJECT WILL DEMONSTRATE THE FEASIBILITY OF A UNIQUE, RAPID, WATER-QUALITY TEST FOR BACTERIA. PHASE I FOCUSES ON THE DEVELOPMENT ...

TAMM RELATES TO TWO TECHNOLOGIES FOR NONINVASIVE TRANSCUTANEOUS MEASUREMENTS OF BLOOD ANALYTES THAT HAVE POTENTIAL FOR APPLICATION IN A COMBAT CASUALTY CARE ENVIRONMENT. THE NEAR INFRARED (NIR) REFLECTANCE TECHNOLOGY DETERMINES BLOOD ANALYTE CONCENTRATION BASED ON DIFFUSE REFLECTANCE MEASUREMENTS WITH A FIBER OPTIC PROBE. SPECTRAL DATA ACQUIRED IS PROCESSED USING SOPHISTICATED PATTERN RECOGNITION ...

MICROBIOLOGICAL MONITORING WILL BE A CRITICAL FUNCTION IN THE BIOMASS-PROCESSING REACTORS OF THE NASA CONTROLLED ECOLOGICAL LIFE SUPPORT SYSTEM (CELSS). MEASUREMENT OF CELLDENSITY AND CELL ACTIVITY IN SOME REACTORS WILL ALLOW FOR THE AUTOMATION AND OPTIMIZATION OF BIOCHEMICAL PROCESSES WITHOUT THE NEED FOR EXPERIENCED SKILLED PERSONNEL. IN OTHER REACTORS, MICROBIOLOGICAL DETECTION AND CHARACTERIZA ...

OPHIDIAN PHARMACEUTICALS PROPOSES TO TEST THE FEASIBILITY OF ADAPTING ITS TECHNOLOGY FOR PRODUCING AND PURIFYING THERAPEUTIC ANTIBODIES FROM THE EGG YOLKS OF HYPERIMMUNIZED LAYING HENS TO THE DEVELOPMENT OF RICIN ANTITOXIN. THIS TECHNOLOGY IS WELL SUITED TO THE RAPID DEVELOPMENT OF TOXIN-NEUTRALIZING THERAPEUTICS AGAINST HIGHLY-VARIABLE TOXINS OR A WIDE VARIETY OF TOXIC THREATS. COMMERCIALLY AVAIL ...

THIS PROJECT PROPOSES TO DEVELOP A TELEROBOTIC CONTROL GLOVE (TCG) FOR THE CONTROL OF ROBOTIC DEXTROUS HANDS. THE GLOVE WILL BE CAPABLE OF CONTROLLING BOTH THE POSITION OF AND THE FORCES EXERTED BY THE FINGERS OF THE ROBOTIC HAND. FEEDBACK OF BOTH TACTILE AND FORCE INFORMATION WILL BE PROVIDED TO THE OPERATOR. THE SYSTEM WILL BE EASILY INTEGRABLE WITH TELEROBOTIC ARM CONTROL SYSTEMS. THE TCG WILL ...

A MAJOR LIMITATION IN CURRENT LARGE SCALE GENOME MAPPING METHODOLOGY IS THAT FEW TOOLS EXIST FOR GENERATING SPECIFIC DNA FRAGMENTS IN THE MEGABASE SIZE RANGE. THIS PHASE I RESEARCH IS EXAMINING THE FEASIBILITY OF DEVELOPING A FAMILYOF INTRON-ENCODED SITE-SPECIFIC ENDONUCLEASES CAPABLE OF GENERATING DNA FRAGMENTS 2 TO 100 MEGABASES IN SIZE BY USINGTHE FOLLOWING STEPS: (1) DEVELOP METHODS FOR EXPRES ...

THIS INNOVATION WILL ADVANCE THE STATE OF THE ART AND PRACTICAL CAPABILITIES OF THERMOGRAPHIC STRESS ANALYSIS (TSA) AND NONDESTRUCTIVE EVALUATION (NDE) TO INVESTIGATE ANDPREDICT THE MECHANICAL BEHAVIORS OF MODELS AND REAL STRUCTURES. A BENCHMARKING METHOD WILL BE ESTABLISHED TO OPTIMIZE STRESS RESOLUTION AND SPEED OF IMAGING. A NEW TSA/NDE SYSTEM BASED ON FOCAL PLANE ARRAY DETECTORS WILL BE DESIGN ...