Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Cloned pigs for Xenotransplantation

    SBC: EVERGEN BIOTECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of the proposed research is to develop methods to create immune protected universal donor cloned transgenic pigs for xenotransplantation. According to the United Network of Organ Sharing (UNOS) more than 30,000 organ transplants are performed in the US alone, yet greater than 95,000 people are currently on the waiting list to receive donors organs f ...

    STTR Phase I 2006 Department of Health and Human Services
  2. Newborn Screening for Sex Chromosome Disorders

    SBC: JS GENETICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Turner syndrome (TS) is the most common genetic problem effecting women, with an incidence of 1 in 1,500 to 2,000 live female births and occurs when an entire, or portions of an X-chromosome is deleted. Phenotypic features include primary hypogonadism, renal abnormalities, and profound short stature. Yet, with growth hormone therapy, acceptable adult stature c ...

    STTR Phase I 2006 Department of Health and Human Services
  3. Modified HER-2 Tumor Antigens for Vaccination in Cancer

    SBC: L2 DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Breast cancer remains one of the most insidious and difficult to treat human malignancies, affecting thousands of individuals each year. Our proposed studies are aimed at developing a novel tumor immunotherapy by using cryptic peptides of Her-2 protein and modified Her-2 peptides, both of which break immune tolerance to ?self? tumor antigens expressed on breast ...

    STTR Phase II 2006 Department of Health and Human Services
  4. Antivirals Targeting Flavivirus Envelope Proteins

    SBC: L2 DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop therapeutic antivirals to treat life-threatening flavivirus infections. Enfuvirtide, a clinically successful peptide HIV fusion inhibitor, is the prototype for a new class of antivirals that inhibit viral envelope protein structural rearrangements essential for viral entry into host cells. In preliminary experiment ...

    STTR Phase I 2006 Department of Health and Human Services
  5. Broad-Spectrum Therapeutic Human Antibodies for Dengue Virus Infections

    SBC: L2 DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop antibody therapeutics to treat life-threatening flavivirus infections. Our working hypothesis is that antibodies recognizing specific, highly conserved envelope protein epitopes can prevent and treat infection by several different flaviviruses, including all four serotypes of dengue virus and West Nile virus (WNV). ...

    STTR Phase I 2006 Department of Health and Human Services
  6. MEMS-Based Aero-optics Simulator System

    SBC: AGILOPTICS            Topic: AF06T030

    This effort joins the MEMS-based deformable mirror technology available from AgilOptics, a New Mexico small business, with the aero-optics technology of the University of Notre Dame to develop an Aero-optics Simulator. This simulator will develop a library of aero-optics patterns to simulate atmospheric distortions for test and evaluation of military or commercial beam control systems.

    STTR Phase I 2006 Department of DefenseAir Force
  7. Targets for RADAR Calibration and Test of Advanced Discrimination Technologies and Concepts

    SBC: Qynergy Corporation            Topic: MDA05T005

    Qynergy Corporation proposes to develop a unique power system for space targets for RADAR calibration and test of advanced discrimination technologies and concepts. There is a need for well-characterized cooperative space targets that can decrease reliance on expensive BMDS integrated flight tests. The space target system would consist of at least 2 objects: a cone of approximately 1-m diameter, ...

    STTR Phase I 2006 Department of DefenseAir Force
  8. Diode Laser-Based Flight Test Instrumentation for Scramjets

    SBC: Southwest Sciences, Inc.            Topic: AF04T012

    This Phase II STTR project will continue the research and development of a simultaneous multi-species sensor system for scramjets flight test instrumentation. The sensor system is based on modulation-frequency multiplexing to combine several laser wavelengths and using a single two-color photodiode detector to collect the laser signals along the same optical path. High-sensitivity detection of c ...

    STTR Phase II 2006 Department of DefenseAir Force
  9. Nanodielectrics Dielectrics for High Power Capacitors

    SBC: TPL, INC.            Topic: AF06T002

    Future power conditioning, control electronics and directed energy weapons will require significant energy storage for a wide range of power applications. Systems will depend on capacitors to deliver high current and high voltage under repetition. In order to find practical embodiment on mobile platforms, significant advances in compact power sources will be required. In response this need, TP ...

    STTR Phase I 2006 Department of DefenseAir Force
  10. Human Protein Kinase Microarrays

    SBC: PROTOMETRIX            Topic: N/A

    DESCRIPTION (provided by applicant): The analysis of protein function has conventionally been done by studying, in depth, a single protein. Recently several groups have initiated efforts to display proteins in two-dimensional array suitable for performing various types of binding studies or assays. In particular, Dr. Snyder's laboratory has developed a microwel ...

    STTR Phase I 2001 Department of Health and Human Services
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