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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Organized Lipid Matrix: Fatty Acids and Choline in CF

    SBC: AVANTI POLAR LIPIDS, INC.            Topic: N/A

    Individuals with cystic fibrosis (CF) and pancreatic insufficiency (PI) are prone to fat malabsorption, putting them at risk for caloric, essential fatty acid, and choline deficiency, which, in turn, may lead to growth failure and a poorer clinical course. Many subjects with CF have essential fatty acid deficiency, characterized by decreased levels of linoleic acid and an increased triene/tetraene ...

    SBIR Phase II 2006 Department of Health and Human Services
  2. Laser Panel Manufacturing Program

    SBC: APPLIED THERMAL SCIENCES            Topic: N04142

    This SBIR Phase II project addresses both the welding of butt joints in plate panels for ships and the manufacture of highly weight-efficient structural sandwich panels for shipbuilding applications. The Phase I project established the technical and financial viability of the Laser/Gas Metal Arc Welding (LGMAW) process to manufacture flat plate blankets ready for further stiffening. A major task ...

    SBIR Phase II 2006 Department of DefenseNavy
  3. Antiviral Drugs for Lassa Fever Virus

    SBC: SIGA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Hemorrhagic fever viruses are of serious worldwide health concern as well as potential biological weapons. Lassa fever virus in particular annually infects several hundred thousand individuals in West Africa, and the export of this pathogen outside of this region, either intentionally or unintentionally, presents a serious risk to the developed countries of the ...

    SBIR Phase II 2006 Department of Health and Human Services
  4. Developing Novel Antibiotics Against Yersinia pestis

    SBC: NOVOBIOTIC PHARMACEUTICALS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop broad-spectrum antibiotics against Yersinia pestis and other important human pathogens. The potential use of engineered, multi-drug-resistant strains as agents of bioterrorism necessitates the development of new anti-Y. pestis therapies. This is a challenging goal, since the last novel class of broad-spectrum antib ...

    SBIR Phase II 2006 Department of Health and Human Services
  5. Interline CCD for Low light Imagery

    SBC: Fairchild Imaging            Topic: A04116

    There is a need to complement the current Gen III image intensifier imaging system with a solid-state low light level camera that is better optimized for remote viewing applications. A silicon-based solution is an ideal candidate for low light imaging because of its high quantum efficiency, low dark current, and excellent uniformity. However, to meet performance requirements under overcast starl ...

    SBIR Phase II 2006 Department of DefenseArmy
  6. Botulinum Toxin Plantibodies

    SBC: Planet Biotechnology Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate goal of the research described in this application is to develop an economical, safe and effective countermeasure to defend the American public from a bioterrorist attack by botulinum toxin. We aim to be the manufacturer of an antibody or antibody mixture, derived form transgenic plants; that win effectively neutralize botulinum toxin and will supp ...

    SBIR Phase II 2006 Department of Health and Human Services
  7. Small Molecule Inhibitors of Smallpox Virus Replication

    SBC: SIGA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Concern over the use of variola virus as a biological weapon has prompted interest in development of small molecule therapeutics for smallpox. Variola virus is highly transmissible and causes severe disease with high mortality rates. Currently, there is no FDA-approved drug for prevention or treatment of smallpox. The overall goal of this smallpox antiviral pro ...

    SBIR Phase II 2006 Department of Health and Human Services
  8. Preclinical Development of LIGO-069-136, An Anti-Inflammatory Pulmonary Therapeut

    SBC: LIGOCYTE PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The LIGO-069-136 Phase II renewal project is a critical path research and development plan designed to qualify an anti-inflammatory monoclonal antibody product for approval of an investigative new drug (INO) for chronic bronchitis. The proposed mechanism of action of LlGO-069-136 is the prevention of neutrophil and monocyte adherence to endothelial cells, and s ...

    SBIR Phase II 2006 Department of Health and Human Services
  9. Shotscreen RPG Defeat System

    SBC: MECHANICAL SOLUTIONS, INCORPORATED            Topic: N04902

    The proposed development project delivers an RPG defeat system for U.S. Marine Corps Light Armored Vehicles. The Shotscreen RPG Defeat system is lightweight compared to competing concepts, and incorporates simplistic technology in an effort to provide a rapid fielding potential and high probability of success. The system releases a wave or screen of shot that collides with the fuze of an incoming ...

    SBIR Phase II 2006 Department of DefenseNavy
  10. Modeling the Impact of Technology Transition on Ship Operational Capabilities

    SBC: Beacon Interactive Systems LLC            Topic: N05053

    During Phase I, we experimented with several transition approaches and ran into three hurdles: 1) No matter how good the method for transitioning technology, if the development process has not been well-managed, there will be no technology to transition; 2) Transition does not happen without an incredible amount of expertise and data; 3) Good technology does not matter if no one is aware of its e ...

    SBIR Phase II 2006 Department of DefenseNavy

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