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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 4379 results
  1. Organized Lipid Matrix: Fatty Acids and Choline in CF

    SBC: AVANTI POLAR LIPIDS, INC.            Topic: N/A

    Individuals with cystic fibrosis (CF) and pancreatic insufficiency (PI) are prone to fat malabsorption, putting them at risk for caloric, essential fatty acid, and choline deficiency, which, in turn, may lead to growth failure and a poorer clinical course. Many subjects with CF have essential fatty acid deficiency, characterized by decreased levels of linoleic acid and an increased triene/tetraene ...

    SBIR Phase II 2006 Department of Health and Human Services
  2. Laser Panel Manufacturing Program

    SBC: APPLIED THERMAL SCIENCES            Topic: N04142

    This SBIR Phase II project addresses both the welding of butt joints in plate panels for ships and the manufacture of highly weight-efficient structural sandwich panels for shipbuilding applications. The Phase I project established the technical and financial viability of the Laser/Gas Metal Arc Welding (LGMAW) process to manufacture flat plate blankets ready for further stiffening. A major task ...

    SBIR Phase II 2006 Department of DefenseNavy
  3. Antiviral Drugs for Lassa Fever Virus

    SBC: SIGA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Hemorrhagic fever viruses are of serious worldwide health concern as well as potential biological weapons. Lassa fever virus in particular annually infects several hundred thousand individuals in West Africa, and the export of this pathogen outside of this region, either intentionally or unintentionally, presents a serious risk to the developed countries of the ...

    SBIR Phase II 2006 Department of Health and Human Services
  4. Developing Novel Antibiotics Against Yersinia pestis

    SBC: NOVOBIOTIC PHARMACEUTICALS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop broad-spectrum antibiotics against Yersinia pestis and other important human pathogens. The potential use of engineered, multi-drug-resistant strains as agents of bioterrorism necessitates the development of new anti-Y. pestis therapies. This is a challenging goal, since the last novel class of broad-spectrum antib ...

    SBIR Phase II 2006 Department of Health and Human Services
  5. Interline CCD for Low light Imagery

    SBC: Fairchild Imaging            Topic: A04116

    There is a need to complement the current Gen III image intensifier imaging system with a solid-state low light level camera that is better optimized for remote viewing applications. A silicon-based solution is an ideal candidate for low light imaging because of its high quantum efficiency, low dark current, and excellent uniformity. However, to meet performance requirements under overcast starl ...

    SBIR Phase II 2006 Department of DefenseArmy
  6. Botulinum Toxin Plantibodies

    SBC: Planet Biotechnology Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): The ultimate goal of the research described in this application is to develop an economical, safe and effective countermeasure to defend the American public from a bioterrorist attack by botulinum toxin. We aim to be the manufacturer of an antibody or antibody mixture, derived form transgenic plants; that win effectively neutralize botulinum toxin and will supp ...

    SBIR Phase II 2006 Department of Health and Human Services
  7. Small Molecule Inhibitors of Smallpox Virus Replication

    SBC: SIGA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Concern over the use of variola virus as a biological weapon has prompted interest in development of small molecule therapeutics for smallpox. Variola virus is highly transmissible and causes severe disease with high mortality rates. Currently, there is no FDA-approved drug for prevention or treatment of smallpox. The overall goal of this smallpox antiviral pro ...

    SBIR Phase II 2006 Department of Health and Human Services
  8. Low Coherence Interferometric Scanning System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: AF093C123

    To address the Air Force need for a new technique for automation of aircraft skin attachment and assembly and Outer Mold Line (OML) control, Physical Optics Corporation (POC) proposed and successfully demonstrated in Phase I a new metrology system for precise thickness measurements of composite panels and fast measurements of steps and gaps between the panels in the aircraft assembly, utilizing a ...

    SBIR Phase II 2011 Department of DefenseAir Force
  9. Electron-Beam Additive Manufacturing Process Control for Titanium Alloys

    SBC: SCIAKY, INC.            Topic: AF091C002

    The proposed scope of work is intended to comprise efforts to implement a production capable Electron Beam Direct Manufacturing (EBDM)system intended to produce parts with sufficient quality and affordability to meet Air Force program requirements. The scope deals not only with the EBDM process specifically but the entire supply chain which is involved with delivering finished titanium aerospace s ...

    SBIR Phase II 2011 Department of DefenseAir Force
  10. A Clinical Trial of Antimicrobial Skin Substitutes for Treatment of Diabetic Ulce

    SBC: Stratatech Corporation            Topic: NIDDK

    DESCRIPTION (provided by applicant): The goal of this Type 2 Competitive Renewal SBIR application to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to conduct a phase I/II clinical trial to investigate the safety and earlyefficacy of a novel antimicrobial living human skin substitute for the treatment of a life-threatening complication of diabetes: chronic, nonhea ...

    SBIR Phase II 2011 Department of Health and Human Services

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