Award Data

DESCRIPTION (provided by applicant): Over 60,000 prosthetic grafts, which are primarily comprised of polyethylene terephthalate (polyester) or expanded polytetrafluoroethylene (ePTFE), are implanted in the United States each year. Unfortunately, these grafts continue to have high failure rates due to secondary complications associated with acute thromboses and incomplete, unregulated cellular prol ...

Non-technical Summary: The profitability of small and mid-sized dairy farms is strongly affected by increases in feed costs and energy costs. Unfortunately, farm operators have limited control of these factors, especially in the long term. New technology is needed to allow farmers to manage energy costs on their farms. One excellent solution is to use existing organic farm waste material to create ...

Requirements for future reconnaissance (Recce) systems are driving the need for very large (~32"x32"), very high quality windows transparent in the visible and Mid Wave Infrared (MWIR) wavebands. At the present time, the leading candidate material for these demanding Recce applications is ALON Optical Ceramic, produced by Surmet Corp. The current available production equipment is limited to fabric ...

Across the services, warfighters are expected to rapidly master new knowledge and skills, spanning wide variety of domains, from motor to cognitive. Traditional training systems generally lack the capability to apply adaptive training strategies that might accelerated learning and develop expertise that endures. While, a number of DoD sponsored programs, including Augmented Cognition and Human Per ...

The Advanced Photon Source (APS) at Argonne National Laboratory (ANL) is a third-generation, high-brightness, 7 GeV storage-ring-based x-ray light source. At present, Argonne is pursuing an APS upgrade project known as the APS Renewal, aiming at improvements through upgrades of beamline optics, detectors, and end-station equipment. Intensive computation is a pivotal aspect of this accelerator mode ...

It is often found that seemingly distinct, scientic codes in elds such as biology, engineering, and physics are faced with the same computational problemthey require the solution of sparse-linear systems arising from the discretization of elliptic and/or parabolic partial dierential equations. This bottleneck can severely hinder the application scientists ability to solve the most challenging prob ...

Available features to detect personas vary depending on the type of intelligence one is observing, and only facets of a persona are observable in each medium. New and enabling technology needs to be developed to search, capture, compare and identify disparate behaviors that may represent personas of interest. In response to this challenge, 21st Century Technologies proposed the Phase 1 Automated C ...

The primary challenges associated with Very High Temperature Reactors (VHTR) stem from their extremely high operating temperatures, especially during accident conditions which way has necessitated new material systems to be developed for most of the core construction, including fuel. There currently exists no method to directly measure peak fuel temperature in emerging Gen-IV reactors. Lambda Inst ...

Citrus canker, caused by Xanthomonas axonopodis pv. citri, a bacteria associated with citrus leafminer (CLM), Phyllocnistis citrella Stainton (Lepidoptera: Gracillariidae) damage, and Huanglongbing (HLB) . Successful completion of this project will provide citrus growers with a valuable tool for managing these two terrifying diseases, and enhance the diagnosis of diseased trees, even in the beginn ...

DESCRIPTION (provided by applicant): Botulinum neurotoxins (BoNTs) are the most toxic substances known to humans, causing respiratory failure. Because of their lethality and ease of production, the Department of Defense (DoD) designates BoNTs as a categoryA bioterrorism agent. Developing effective, post-exposure antagonists to BoNT is among DoD's top priorities. Despite their lethality, BoNT ...