Award Data

This Small Business Innovation Research (SBIR) Phase II project will further develop a fully hardened, user friendly ASL Pichia monitor for commercial protein production. The Phase I effort demonstrated the commercial feasibility of the continuous, real-time near infrared monitor for tracking metabolite levels and cell density during protein expression with Pichia pastoris. Implementing this techn ...

DESCRIPTION (provided by applicant): Atherosclerosis is the primary cause of cardiovascular disease, which is the most common cause of death in the United States. Atherosclerosis is characterized by the accumulation of lipids, cholesterol, calcium deposits, and cellular debris in vessel walls, and results in plaque formation, arterial obstruction, and diminished blood flow to organs. These plaques ...

Development of an energy harvesting system utilizing the magnetostrictive material, Galfenol, will be completed in this effort. The energy harvesting system will consist of Galfenol plates or sheets, magnetic circuit components, coupling structure, power conditioning electronics, sensor, and wireless transmitter. Lab testing and relevant environment testing through sea-trials will be completed on ...

Currently there are no truly effective interventions or therapeutic treatments for White spot syndrome virus (WSSV) in farmed shrimp. Current production practices focus on pathogen exclusion by stocking specific pathogen free (SPF) larvae, decontamination and filtration of water to prevent pathogen introduction, and strict biosecurity at hatcheries and grow out pond sites. This is extremely challe ...

Etrema is developing an acoustic projector that provides broad bandwidth, high source level, directional output, high duty cycle, and high reliability in a compact package. Specific objectives of the Phase II effort are: demonstrate performance of a prototype projector, optimize the full-scale projector design, and demonstrate performance of the full-scale projector. Fabrication and testing of the ...