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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 151037 results
  1. Brain-enriched microRNAs detectable in plasma as biomarkers of Alzheimer's disease

    SBC: DIAMIR, LLC            Topic: NIA

    SUMMARY About of Americans age have Mild Cognitive Impairment MCI of which progress to dementia annually A growing number of companies are developing new therapeutics aiming to intervene early in the development of Alzheimerandapos s disease the most common form of dementia and there is a great need for accurate minimally invasive diagnostics for primary screening of individ ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Pre-Clinical Development of Topical Pirenzepine for Treating Diabetic Neuropathy

    SBC: WINSANTOR, INC.            Topic: 200

    DESCRIPTION provided by applicant The objective of this SBIR fast track project is to expediently advance pre clinical development of a new therapeutic for diabetic neuropathy Of the million Americans who suffer from diabetes approximately will be diagnosed with neuropathy which is characterized by nerve degeneration Despite the high prevalence of the disease there is currently no F ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Clinical Evaluation of a Resorbable Vena Cava Filter

    SBC: ADIENT MEDICAL, INC.            Topic: NHLBI

    PROJECT SUMMARY Clinical Evaluation of a Resorbable Inferior Vena Cava Filter Pulmonary embolism PE is the rd leading cause of death claiming the lives of at least Americans annually more than breast cancer AIDS and vehicle fatalities combined Metallic Inferior Vena Cava IVC filters have been proven effective in reducing PE to about in at risk populations however they ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Correlating TCR diversity to immune reconstitution after cord blood transplant

    SBC: ADAPTIVE BIOTECHNOLOGIES CORPORATION            Topic: NHLBI

    DESCRIPTION provided by applicant Many patients requiring stem cell transplantation for hematological malignancies are unable to find a suitable HLA matched sibling or unrelated donor Transplants using stem cells from umbilical cord blood provide an alternative for these patients allowing transplantation to proceed with less stringent HLA matching requirements Unfortunately in addition to t ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Web Application and Services for Methodologically Rigorous Animal Study Design

    SBC: TEMPEST TECHNOLOGIES            Topic: NIDA

    DESCRIPTION Our goal in this project is to develop a web application to guide researchers in the efficient and effective design of animal studies that balance the competing needs of minimizing animal use and providing rigorous repeatable results Three basic ideas which translate directly into our three specific aims form the foundation of our proposed tool First an foremost is to place scie ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. An Integrated Microarray Printing and Detection System

    SBC: BIOSENSING INSTRUMENT, INC.            Topic: 400

    DESCRIPTION provided by applicant Microarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugs Typically protein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another device During each testing cycle the entire microarray becomes expos ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Service and Software Solution for the Rigorous Design of Animal Studies

    SBC: SERALOGIX            Topic: NIDA

    The primary goal of this fast track project is to commercialize a cloud based software suite complemented with on call expert services to guide life science researchers that may have minimal statistical and experimental design ED knowledge to rigorously plan optimize justify manage and report results for complex animal studies Inadequately planned experiments e g lack of randomization b ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. SBIR Phase II: Sustainable Rare Earth Element Recycling from Neodymium Magnets

    SBC: Rare Resource Recycling            Topic: MI

    The Small Business Innovation Research (SBIR) Phase II project will implement a proprietary rare earth extraction process on recycled NdFeB magnets at pilot scale to prove commercial production feasibility. By recovering rare earth elements (REEs) readily available in waste streams, this effort will help create a secondary source of these critical elements, thereby reducing U.S. dependence on an u ...

    SBIR Phase II 2017 National Science Foundation
  9. SBIR Phase II: Zero Thermal Expansion Alloys For Lasers

    SBC: Thermal Expansion Solutions, LLC            Topic: MI

    This Small Business Innovation Research (SBIR) Phase II project will develop new alloys whose thermal expansion properties can be tailored for laser applications. The tailored thermal expansion alloys will prevent shifts in laser output frequencies, i.e. laser color, by preventing the natural temperature-induced thermal expansion and contraction that occurs in laser housings. This temperature stab ...

    SBIR Phase II 2017 National Science Foundation
  10. SBIR Phase I: Affordable On-Demand Additive Manufacturing

    SBC: ThinkIncubate, Inc.            Topic: MN

    This SBIR Phase I project will develop a proof-of-concept for a new approach in the field of Additive Manufacturing (AM). Pioneered few decades ago, AM has the potential to enable the manufacture of products from the inside out, enabling the production of lighter products with higher structural integrity than is possible with conventional subtractive manufacturing techniques. However, legacy AM ap ...

    SBIR Phase I 2017 National Science Foundation

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