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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Multifunctional Antioxidant to Prevent Noise-Induced Hearing Loss

    SBC: Therapeutic Vision, Inc.            Topic: NIDCD

    Noise induced hearing lossNIHLis the most common occupational disease for which no clinically effective drug is availableSince NIHL involves oxidation linked loss of sensory hair cells and auditory neurons in the cochleathere is a need for potent and effective antioxidants that offer protection to these tissuesIn preliminary studies we have observed that the orally administered multifunctional ant ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Seromic Mucin Signature for the Early Diagnosis of Pancreatic Cancer

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 102

    ABSTRACT Pancreatic cancerPCis an extremely aggressive malignancy with one of the worst prognoses of all cancersWith marked resistance to chemoand radiotherapiessurgery is the only curative optionIn patients with localized diseasecomplete surgical resection provides five year survival rate ofHoweverandgtof patients are diagnosed with unresectable primary tumors and or distant metastasisThe major c ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. MUC4/16 assay for the early diagnosis and management of benign and malignant pancreatic diseases

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 300

    Abstract The goal of this Fast track application is to develop a non invasive diagnostic testbased on MUCand MUCmucinsthat can serve as an adjunct to cytological analysis of fine needle aspiratesFNAsfor accurate prediction of malignancy in patients with cystic pancreatic lesionsDue to asymptomatic nature and lack of methods for early detectionandgtof pancreatic cancerPCpatients present with an unr ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Seromic Mucin Signature for the Early Diagnosis of Pancreatic Cancer

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 102

    ABSTRACT Pancreatic cancerPCis an extremely aggressive malignancy with one of the worst prognoses of all cancersWith marked resistance to chemoand radiotherapiessurgery is the only curative optionIn patients with localized diseasecomplete surgical resection provides five year survival rate ofHoweverandgtof patients are diagnosed with unresectable primary tumors and or distant metastasisThe major c ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Rapid mRNA Expression Analysis by Quantitative Electrochemical Microarray at Sub-Zeptomole Levels without PCR and Labels

    SBC: VAJRA INSTRUMENTS, INC.            Topic: NHGRI

    Methods for obtaining transcriptome data have revolutionized our understanding of biological processes and disease dynamics at the fundamental levelimpacting health care on all three frontsdiagnosticsprognosticsand therapeuticsThe compiling of transcriptome informationat one end of the spectrum leads to discovery of genes and mutations usingfor examplethe Sanger method and NetGen sequencingand at ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Prognostic Blood Test to Monitor Pancreatic Cancer Treatment by MiRNA Profiling

    SBC: VAJRA INSTRUMENTS, INC.            Topic: 102

    Pancreatic ductal adenocarcinomaPDAChas ayear survival rate of less thanThe success in developing therapies for other cancers over the last two decades has not improved the dismal overall survivalOSrate for PDACIt is now becoming increasingly apparent that personalized medicine based on the genetics of a tumor will be essential for developing a treatment strategyThusthere is an urgent need to deve ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Fuel Efficiency Improvements for Amphibious Vehicles

    SBC: PACIFIC ENGINEERING, INC.            Topic: N162079

    This Phase II project goal is to develop solutions that improve the fuel efficiency of Amphibious Vehicles. Amphibious vehicles operate on the leading edge of an assault and in environments where ongoing access to fuel is limited. More efficient fuel usage will also enable longer mission durations and increased operating ranges. The goal is to reduce fuel usage over the Amphibious Vehicle mission ...

    SBIR Phase II 2018 Department of DefenseNavy
  8. SBIR Phase II: Novel Device for Maintaining Continuous Fluid Drainage in Small-Bore Chest Tubes after Cardiothoracic Surgery

    SBC: ESCULON LLC            Topic: BM

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to significantly improve outcomes for cardiothoracic surgical patients while reducing healthcare costs by ensuring proper post-surgical drainage. In the United States, approximately 750,000 major cardiothoracic surgeries are performed each year. Each of these patients receives an average o ...

    SBIR Phase II 2017 National Science Foundation
  9. Next Generation Western for high-throughput and high-content protein analysis

    SBC: LI-COR, Inc.            Topic: 400

    Abstract The identification and quantification of specific proteins in complex samples are critical processes in discoveringunderstandingand ultimately addressingthe underlying nature of human health and diseaseThe western blot is a fundamental method used for these processes due to the sensitivity and specificity enabled by combining protein sizing with immuno detectionDespite being widelyusedthe ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Community College- Technical School Intelligent Transportation Systems (ITS) Curricula

    SBC: Integrated Global Dimensions LLC            Topic: 151FH2

    Transportation Tech is the development and implementation of an online, on‐demand educational curricula for Intelligent Transportation Systems (ITS) and Connected Vehicle (CV) technology. Transportation Tech content is designed and developed to encourage students to choose careers in ITS as well as train current ITS and CV technicians in the field. Through customized portals, at the end of the P ...

    SBIR Phase II 2017 Department of Transportation
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