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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 3075 results
  1. Inexpensive, sensitive and specific, point-of-care diagnostic for bacterial infections in the central nervous system

    SBC: CNINE BIOSOLUTIONS, INC.            Topic: NIAID

    The objective of this Phase I application is to develop and assess a sMAC lateral flow assay diagnostic tool for bacterial meningitis BM Development of rapid highly sensitive and specific clinical diagnostic for bacterial infections in the central nervous system CNS such as BM and shunt infection that are easy to use and cost effective would significantly improve healthcare in the US and ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Genotyped and Single Cyst-derived Human ADPKD Cell Platforms for Industry and Academia

    SBC: DISCOVERYBIOMED, INC.            Topic: 100

    DiscoveryBioMed Inc DBM Inc or DBM specializes in normal and diseased human cell platform engineering DBM has assembled a consortium of experts whereby collectively we seek Fast Track SBIR funding to establish and offer a Product Line Menu of normal and ADPKD human cell platforms for the academic and industry marketplaces Existing and interested DBM clients will be presented in terms of ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. SBIR Phase I: Bridging the Education Gap Between Block-Based Programs and Cryptic C++ Code with an Internet of Things Based Interactive Code Development and Debug Platform

    SBC: Firia, Inc.            Topic: EA

    This SBIR Phase I project will develop a low cost educational platform which provides students a gateway to understanding and writing software code in modern real-world programming languages. The research addresses a pressing need in the K-12 setting to engage both teachers and students in Coding as a Literacy. Current approaches to teaching computer science and programming principles in K-12 ofte ...

    SBIR Phase I 2017 National Science Foundation
  4. Advanced Metallic-Silicon Carbide Composite Claddings for Improved Damage Tolerance

    SBC: Plasma Processes LLC.            Topic: 29b

    The recent events at the Fukushima nuclear power plant highlight the need for enhanced accident tolerance. Of particular concern is the overheating of standard zirconium alloy cladding in a loss of coolant accident (LOCA). One of the leading, high-risk/high-reward candidates for future claddings is a silicon carbide (SiC) composite. However, the inherent open porosity present in fibrous based comp ...

    SBIR Phase I 2017 Department of Energy
  5. Demonstration of the technological capability for production of neutron-focusing nickel mirrors

    SBC: Electroformed Nickel            Topic: 08a

    Neutron scattering is one of the most useful methods of studying the structure and dynamics of matter. Therefore, a number of new large neutron facilities have recently being constructed, upgraded or planned around the world. Examples include the new, 1.4 billion-dollars Spallation Neutron Source (SNS) at DoE’s Oak Ridge National Laboratory (ORNL) and upgrades of ORNL’s High-Flux Isotope React ...

    STTR Phase I 2017 Department of Energy
  6. Multi-Scale In Vitro 3D Tissue Model of Vascularized Bone-Cartilage Interactions

    SBC: CFD RESEARCH CORPORATION            Topic: NIAMS

    Abstract Current in vitro models of vascularized bone tissues do not mimic the in vivo microenvironment comprising of diverse cell types in communication with each other through stromal barriers In addition they are hampered by lack of real time visualization and quantitation of vasculature bone as well as bone cartilage interactions In contrast animal models while providing useful information ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Oral formulation for novel inhibitor of Ras driven cancers

    SBC: ADT PHARMACEUTICALS, LLC            Topic: 102

    Mutations in the ras family of genes were first identified in human cancer over years ago Such mutations may result in the constitutive activation of one or more of three major Ras protein isoforms including H Ras NRas or K Ras that mediate important signaling pathways leading to uncontrolled cell growth and tumor development Activating mutations of ras genes occur de novo in approximatel ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Coating to enhance endothelialization after left atrial appendage closure

    SBC: ENDOMIMETICS, LLC            Topic: NHLBI

    The prevalence of atrial fibrillation in the US is approximately to million putting patients at significantly increased risk of cardioembolic stroke Approximately of all strokes are caused by atrial fibrillation Most atrial fibrillation is treated with blood thinners however some patients are at such high risk of bleeding that it prohibits anticoagulation Left atrial appendage ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Endotoxin Neutralization as a Biomonitor for HIV Disease Progression

    SBC: BIODTECH, INC.            Topic: NIAID

    ABSTRACT Endotoxin neutralization in human plasma is an excellent indicator of chronic immune activation which is an accurate predictor of mortality in HIV infection Recently we developed an assay using endotoxin neutralization as an indicator of immune activation due to bacterial translocation This assay is accurate in discriminating healthy patients from those with inflammatory bowel disea ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Humanized Kidney Cellular Toxicity Platforms

    SBC: DISCOVERYBIOMED, INC.            Topic: NIEHS

    Principal Investigators for Small Business DiscoveryBioMed Inc DBM Project Summary Abstract The over arching goal of this proposed SBIR driven program is to create relevant DiscoveryBioMed DBM human cellular toxicity HCT platforms for the kidney grown in D and in D cell culture formats for a new gold standard in lead therapeutic asset and materials in vitro testing and to reduce marke ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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