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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Development of the first thermolytic to suppress shivering and seizure

    SBC: Be Cool Pharmaceutics LLC            Topic: NHLBI

    Summary The temperature management market is expected to reach $ billion by yet no pharmaceutical has yet been developed specifically for this market A adenosine A AR agonists are well known to attenuate seizure and protect the brain from injury but development of these drugs has been limited by side effects including hypothermia bradycardia and hypotension Inspired by our discover ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Nutritional Therapy in Elderly with Heart Failure

    SBC: Essential Blends, LLC            Topic: NIA

    Project Summary Abstract We have developed a nutritional formulation of amino acids called UpBeat that is designed to promote physical function and quality of life in older individuals with heart failureReduced exercise capacity is a prominent clinical feature of heart failureThis leads to progressive muscle weakness and a vicious cycle of sedentary behaviorweight gainand subsequent development of ...

    STTR Phase II 2017 Department of Health and Human Services
  3. Nutritional Therapy in Elderly with Heart Failure

    SBC: Essential Blends, LLC            Topic: NIA

    DESCRIPTION provided by applicant The long term goal of this project is to develop and test a nutritional product that will improve physical function in individuals with heart failure H in the geriatric population Our approach to nutritional therapy NT focuses on increasing skeletal muscle strength improving vascular reactivity and optimizing regulation of energy substrate metabolism All ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Muscle preservation during weight loss in older, overweight individuals

    SBC: Essential Blends, LLC            Topic: N

    DESCRIPTION provided by applicant The overall goal of this project is to test a meal replacement beverage that will ultimately preserve muscle loss during calorie restriction weight loss CRWL in obese older individuals We previously developed a meal replacement rich with a proprietary blend of essential amino acids TMR that was more than three times as effective as whey protein in stimulat ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Identification of Patients with Clostridium Difficile Infection, Colonization and/or Reoccurrence

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    Clostridium difficile infection (CDI) results in excess of 14,000 deaths and over $1 billion in excess healthcare costs annually. Early and reliable diagnosis is key for both improving treatment outcomes, and instituting precautions to prevent transmission. Antibiotic therapy can actually increase the odds of coming down with a hospital-acquired infection, especially when the cause is a bacterium ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. National Phone App for Linking Adolescents to Local Pregnancy Prevention Resources

    SBC: NATIONAL HEALTH PROMOTION ASSOCIATES, INC            Topic: N/A

    Teen pregnancy rates remain high particularly among racial/ethnic minority youth and age of onset for sexual activity has decreased significantly in recent years. As young teenagers initiate dating and sexual activity during the years of middle school, there are often few resources available for accurate information about pregnancy prevention and reproductive health. Furthermore, teens may not kno ...

    SBIR Phase I 2013 Department of Health and Human Services
  7. Multi-Media Imagery Program for Breast Cancer Patients (Phase II)

    SBC: MIND MATTERS RESEARCH            Topic: N/A

    DESCRIPTION (provided by applicant): To improve quality of life and reduce stress for breast cancer survivors. Phase II Aims: (1) To demonstrate the clinical efficacy (i.e., improved quality of life, stress reduction, participant satisfaction with product) of the Envision the Rhythms of Life program and (2) to establish the technical merits of the program's distance-delivery (videoconferencing ...

    SBIR Phase II 2008 Department of Health and Human Services
  8. Multi-Media Imagery Program for Breast Cancer Patients

    SBC: MIND MATTERS RESEARCH            Topic: N/A

    DESCRIPTION (provided by applicant): The specific aim of this Phase I SBIR project is to establish the technical merit and feasibility of producing a modular imagery intervention program for breast cancer patients and survivors that can be delivered to patients in a classroom setting, and/or at-a-distance, via Internet. Phase I prototype will emphasize feasibility of delivery and potential efficac ...

    SBIR Phase I 2005 Department of Health and Human Services
  9. EVALUATION OF ALASKAN PLANTS FOR TUBERCULOSIS TREATMENT

    SBC: Alaska Green Gold Company            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal aims to evaluate the efficacy of Native American ethnobotanical treatments for tuberculosis for the purpose of making available acceptable, affordable alternatives to current TB drugs, especially in developing countries with massive TB case loads such as the People's Republic of China. No new drugs have been introduced for the treatment of tuberc ...

    SBIR Phase I 2003 Department of Health and Human Services
  10. Disinfectant Efficacy on Surface Bacteria and Biofilms

    SBC: MICROBION CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Grant Phase I project is investigating an innovative disinfectant product designed to improve on the limited efficacy of disinfectants used in hospitals. This research is based on the fact that inanimate surfaces in clinical environments frequently harbor viable, pathogenic, and often drug-resistant microorganisms. These ...

    SBIR Phase I 2003 Department of Health and Human Services

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