Award Data

FOR MORE THAN TWENTY-FIVE YEARS THE BIOLOGICAL SCIENCES CURRICULUM STUDY (BSCS) HAS BEEN PRODUCING HIGH QUALITY ORIGINAL ARTWORK AND PHOTOGRAPHS AS AN INTEGRAL PART OF ITS MANY EXEMPLAR EDUCATIONAL PROGRAMS. THIS BIOLOGICAL VISUAL LIBRARY MOST LIKELY CONTAINS THE GREATEST COLLECTION OF BIOLOGICAL ARTWORK ANYWHERE IN THE WORLD. ITS VALUE IS IN THE MILLIONS OF DOLLARS. LASER VIDEODISC TECHNOLOGY MAK ...

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DESCRIPTION (provided by applicant): Innovations in battery technology and microelectronics are now finding wide acceptance in the design of new prosthetic and orthotic appliances, while the actuators used to produce motion and force in these devices remain essentially unimproved. The overall goal of this multi-phase, expanded SBIR project is to adapt a new class of "active" materials--developed t ...

DESCRIPTION (provided by applicant): According to the U.S. Bureau of the Census, approximately 7.7 million people over the age of 15 report they are unable to lift or carry even 10 pounds with their arms because of neuromuscular impairments. Extensive research suggests that "powered orthoses" could provide great benefit to many of these individuals. Comprised essentially of an orthotic brace fitt ...

DESCRIPTION (provided by applicant): This proposal aims to evaluate the efficacy of Native American ethnobotanical treatments for tuberculosis for the purpose of making available acceptable, affordable alternatives to current TB drugs, especially in developing countries with massive TB case loads such as the People's Republic of China. No new drugs have been introduced for the treatment of tuberc ...

DESCRIPTION (provided by applicant): Clot formation and dissolution are essential to human survival. Abnormal clot formation and occlusion of blood vessels of the heart, lung, brain, and peripheral circulation can result in death, incapacitation, and limb amputation. Rapid treatment with thrombolytic agents to dissolve clots and restore blood flow is a means to minimize morbidity and mortality i ...

DESCRIPTION (provided by applicant): With a daily production capacity of two grams of protein per egg, the chicken ovalbumin gene locus has the potential to synthesize large amounts of biopharmaceutical proteins into the eggs of transgenic hens. This phase I SBIR project will test the feasibility of using large expression constructs, based on the complete 200 kilobase chicken ovalbumin gene locus, ...

DESCRIPTION (provided by applicant): Parenteral administration of insulin via the subcutaneous route is the only commercially available therapy to treat insulin-dependent diabetes mellitus. Multiple daily injections are required to manage and maintain blood glucose control due to its relatively short duration of action (4 to 8 hours). Oral insulin would provide an attractive alternative. However, ...

DESCRIPTION (provided by applicant): Interleukin 11 (IL-11) is a cytokine that stimulates proliferation, maturation and functional activation of platelets. Recombinant human IL- 11 is approved and marketed as a treatment for thrombocytopenia in certain patients undergoing myelosuppressive cancer chemotherapy, the market for which is estimated to be $500 million. IL-11 has a short in vivo half-life ...