Award Data

TDAs proposes to develop a novel RF heating process for rewarming cryogenically preserved tissues and organs. TDAs approach is to optimize the RF frequency and power, along with the chemical composition, size and morphology of infused nanoparticles so that they heat tissue samples rapidly and uniformly. In this manner, the cryoprotectant solutions pass from the vitrified state to the liquid stat ...

Atmospheric aerosols, also known as particulate matter (PM), play important roles in weather, climate and human health. Aerosol number, size and chemistry can all exhibit high degrees of spatial and temporal variability, thereby increasing the need for highly time-resolved analyses obtained over extensive time periods (weeks to years). Instrumentation for monitoring the physical characteristics of ...

Polyurethanes (PUs) are made by reacting two components, one of which has two or more hydroxyl (OH) groups (diol or polyol) while the second has two or more isocyanate (NCO) groups. Unfortunately, not only is the isocyanate component a powerful irritant, but sensitized subjects can suffer severe asthma attacks and even death when exposed to trace quantities that are well below permissible exposure ...

Small drinking water systems consistently provide safe, reliable drinking water to their customers. However, challenges of such systems include lack of financial resources, aging infrastructure, cost of scale, and technical/logistical challenges associated with regulation compliance. The deployment of new cost-effective monitoring technologies, such as improved, low cost, in-line, in situ, and rem ...

Military personnel must be protected from diseases transmitted by ticks and fleas, including Lyme disease. Effective surveillance of tick and flea vectors is vital to determine the population present, whether they are carrying disease, and whether control campaigns are working. Unfortunately, current surveillance tools are ineffective. In Phase I TDA designed, prototyped, and tested a novel ti ...

Civilian and military organizations throughout the world perform surveillance to combat vector-borne disease. Of particular concern to the U.S. military are mosquito genera Anopheles, Aedes and Culex, which are important vectors for malaria, dengue and West Nile virus respectively, and sand fly genera Phlebotomus and Lutzomyia, both vectors for leishmaniasis. The trap most commonly used for by U.S ...

The objective of this proposed project and the EPA Computational Toxicology program’s goals are aligned in assessing chemicals for potential risk to human health and the environment through the use of more representative multicellular human developmental neurotoxicology assays. ArunA Biomedical will develop a rapid, scalable, human pluripoten stem cell derived cell-based co-culture assay system ...

The release of chemical and biological agents on a large scale urban environment would be devastating. The amount of waste generated during such an event would be comparable to a tornado ripping through a town. Building materials, furniture, office materials, building insulation, wood structures could become contaminated to a level that they could not be decontaminated without their destruction. ...

Large farms and feedlot operations produce large quantities of manure in a small area. Anaerobic digester units capable of producing pipeline quality methane installed at each farm or dairy could be instrumental in eliminating the difficulties associated with the transport of manure off site. If consumed properly, use of manure-derived fuels can also protect against environmental problems such as ...

This Small Business Innovation Research (SBIR) Phase II project will employ the large scale; highly reliable boron-doped ultrananocrystalline diamond (BD-UNCD®) electrodes developed during Phase I project to build and test Electrochemical Anodic Oxidation process (EAOP) cells and systems that can destroy Contaminants of Emerging Concern more economically and effectively than competing AOPs. BD-UN ...