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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Embedded Access to Signing of Science Terms and Definitions

    SBC: VCOM3D INC            Topic: NA

    Deaf and hard-of-hearing students may lag behind their hearing peers in English literacy and in science, technology, engineering, and mathematics (STEM). Evaluations in classroom and informal environments have demonstrated the efficacy of the dictionaries in increasing student engagement and mastery of math and science content and vocabulary. This project develops a cloud-based service and corresp ...

    SBIR Phase I 2015 Department of Health and Human ServicesAdministration for Community Living
  2. Manufacturing pathogen inactivated platelet lysate to treat corneal inflammation

    SBC: Cambium Medical Technologies LLC            Topic: N

    DESCRIPTION provided by applicant Ocular graft versus host disease O GVHD is a particularly severe and debilitating complication of allogeneic hematopoietic stem cell transplantation HSCT O GVHD develops in of patients with chronic GVHD Currently Restasis cyclosporine A is the only FDA approved prescription topical medication to treat O GVHD In Restasis had sales o ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Selenium-derivatized New Reagents for Nucleic Acid X-ray Crystallography

    SBC: SENA RESEARCH, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant There are growing demands for D structure determination of nucleic acids and their protein complexes for understanding disease molecule level mechanisms and discovering innovative drugs X ray crystallography is one of the most direct and powerful tools for structure determination of these macromolecules and complexes However the crystallization and phase d ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Novel selective alpha4beta2 nicotinic receptor antagonists for smoking cessation

    SBC: ASSUAGE PHARMACEUTICALS, INC.            Topic: NIDA

    DESCRIPTION provided by applicant Smoking remains the number one avoidable cause of death in the United States and costs the economy tens of billions of dollars every year Current therapies include nicotine replacement with a patch or gum inhibition of the dopamine system with bupropion and partial activation of the neuronal nicotinic acetylcholine receptor nAChR with varenicline Non ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Combination Immunotherapy of a Novel Superagonist IL-15 Complex and Anti-CD20 Antibody for Indolent Non-Hodgkin Lymphoma

    SBC: Altor BioScience, LLC            Topic: 102

    DESCRIPTION provided by applicant Non Hodgkin lymphoma NHL is the most commonly diagnosed hematologic malignancy in the U S with over new cases and about deaths due to NHL expected in Over one third of all cases are slow growing or indolent NHL iNHL which affect older adults and typically present as advanced disease The initial treatment of iNHL consists of an anti CD ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Location-based Smartphone Technology to Guide College Students??? Healthy Choices Phase II

    SBC: KLEIN BUENDEL, INC.            Topic: NCCDPHP

    DESCRIPTION provided by applicant Poor eating habits sedentary behavior and deficient sleep quality are problematic for many college students Surrounded by numerous unhealthy food choices and physical activity barriers students are vulnerable to overweight and chronic diseases such as diabetes heart disease and cancer Todayandapos s college students are more technologically connected tha ...

    SBIR Phase II 2015 Department of Health and Human ServicesCenters for Disease Control and Prevention
  7. Discrete Event Simulation and Optimization Approach for Balancing Usability and Security for Medical Devices in an Integrated Clinical Environment

    SBC: Design Interactive, Inc.            Topic: DHP15005

    Integrated clinical environments (ICEs) include medical devices and systems that process, store, and share sensitive data over networks. This requires that security concerns and data privacy be addressed. However, the design of such controls can conflict with the usability of the medical devices, especially in high pressure, time-sensitive conditions such as acute clinical and remote care settings ...

    SBIR Phase I 2015 Department of DefenseDefense Health Agency
  8. Receptors, Ligands, and Catalysts on Demand using Expanded Genetic Alphabets

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: 100

    DESCRIPTION provided by applicant Technology to deliver molecules andquot on demandandquot that bind to targets or catalyze reactions of a technologistandapos s choosing would have enormous commercial value in research manufacturing and medicine Thus this has been a andquot holy grailandquot of molecular science for a half century Even today chemical theory is inadequate to support de ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Kits for high-multiplexed detection of RNA viruses in complex biological samples

    SBC: FIREBIRD BIOMOLECULAR SCIENCES LLC            Topic: 300

    DESCRIPTION provided by applicant The public health challenges from RNA viruses are at a tipping point with dengue moving up Florida human transmission of chickungunya now established in Florida and transmitted by different mechanism Ebola While these have long been a challenge their incidence has been predominantly overseas In addition the health hazards of other RNA viruses better k ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Connecting Cultures and Technology: Addressing Disparities in Mental Health Intervention for Refugees

    SBC: GAMETHEORY, INC            Topic: NIMHD

    DESCRIPTION provided by applicant Thousands of individuals seek refuge in the United States to escape atrocities of war and torture in their country of origin An overwhelming majority of these individuals continue to struggle with Chronic Traumatic Stress CTS the persistence of prior traumatic events e g re experiencing past trauma coupled with daily post migration stressors e g pove ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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