Award Data

Uncertainty quantification (UQ) can be performed with existing MDA M&S tools if efficient algorithms are developed and deployed. OptTek proposes to explore innovative methods and algorithms to 1) quantify output variation from all input uncertainties providing distributional information and extreme value identification, 2) isolate output variation from individual input uncertainties and from input ...

Inspecting for and detecting counterfeit, unapproved material substitutions or substandard processed raw material using existing processes is difficult, time consuming and expensive.Ocean Bay, LLC and the Primary Investigator, Karen Bruer, formed a team consisting of Ocean Bay, LLC, Savanah River National Laboratory and Old Dominion University, to apply for DLA15C-001:Detecting Substandard, Noncon ...

Septic shock is a significant worldwide health problem that affects millions, but is complicated to treat since many of the signs and symptoms are non-specific and common to other non-infectious sources of systemic shock. Patient care would be improved by a rapid test to monitor key biomarkers and determine whether antibiotic use is appropriate. We propose to deliver a quantitative, multiplexed ...

SIFT, along with Drs. Julie Adams and Ramesh Sagili of Oregon State University (OSU), propose to develop Resilient Emergent Properties for Autonomous Agent InteRactions (REPAIR). Building upon recent innovative work in swarm control and optimization, and applying new observations of specific defensive and adaptive characteristics of honeybee colonies, REPAIR will provide biologically inspired meta ...

Rapid design and prototyping of systems and components needed by the DoD include the need for accurate models of non-linear and time-dependent magnetic circuit components, that provide advanced circuit capabilities for improved communications and remote sensing applications. Simulation of circuits using RF computational engines work well in the linear regime, but are inaccurate for non-linear and ...

Future, large footprint weapon systems can benefit from inexpensive telemetry collection assets that could be easily and quickly deployed in open-ocean and could either store the data for later pickup, or retransmit the data either on command from shore or autonomously. A low-cost telemetry collection system on buoys would enable development, testing, and evaluation of new weapon systems using rea ...

DARPA has embarked on the Experimental Spaceplane (XS-1) program to facilitate rapid insertion of smallsat payloads at aircraft-like operational tempos. An enabling technology for minimizing the cost and maximizing the payload-to-space capability of XS-1is reusable, all-composite, liner-less (Type V) cryogenic tanks with very low mass fractions. DARPA has identified that current material limitat ...

We propose to develop NeuroDAS (Neuroscience Data Archiving and Sharing), a validated, supported, and fully documented next-generation management and sharing commercial system for complex neuroscience data. NeuroDAS will allow the implementation of secur...

As the human population grows, it is critical to decrease consumption materials from the planet and its ecosphere. The world adds 70 million people annually. The UN expects the population to grow to over 9 billion 2050. Climate change, soil degradation, ...

This proposal leverages our expertise in genetic engineering in general, our success in multiplex gene editing, and nanoparticle-based gene delivery to achieve targeted base editing of hepatitis B virus (HBV) genomes in infected cells. Not only will this...