Award Data

This project focuses on developing a magnetic resonance imaging (MRI) contrast agent that may increase the detection of tagged cells by a factor of 10-100. The ability to noninvasively track specifically labeled (tagged) cells, enables a researcher or medical treatment professional to dynamically monitor the delivery and targeted application of medicinal and bio-reactive agents.

Magnetic resonance imaging (MRI) has become a primary diagnostic tool in scientific research and clinical imaging. Despite the excellent image quality that can be obtained with today’s MRIs, images acquired using different MRI systems and during longitudinal studies are not reproducible, and hence can be difficult, if not impossible, to compare. To address this issue, a standardized test of the ...

Health Delivery Organizations, including the Military Health System, are increasingly using networked medical devices to benefit from improved information accuracy, lowered costs, and improved patient outcomes. These benefits, however, are threatened by the security risks posed by the interactions between the networked devices, and their connection to IT systems which are at risk of cyber attack. ...

TDAs proposes to develop a novel RF heating process for rewarming cryogenically preserved tissues and organs. TDAs approach is to optimize the RF frequency and power, along with the chemical composition, size and morphology of infused nanoparticles so that they heat tissue samples rapidly and uniformly. In this manner, the cryoprotectant solutions pass from the vitrified state to the liquid stat ...

We propose a novel high efficiency (≈40%) generator system capable of providing 1 kWe along with hot water on-demand. The integration of two novel concepts: 1) an internal combustion engine (ICE) operating on Spark-Assisted Compression Ignition (SACI) combustion of natural gas (NG), and 2) a bottoming Organic Rankine Cycle (ORC) with waste energy recovery (WER) from ICE exhaust enables the overa ...

We propose a novel high efficiency (≈40%) generator system capable of providing 1 kWe along with hot water on-demand. The integration of two novel concepts: 1) an internal combustion engine (ICE) operating on Spark-Assisted Compression Ignition (SACI) combustion of natural gas (NG), and 2) a bottoming Organic Rankine Cycle (ORC) with waste energy recovery (WER) from ICE exhaust enables the overa ...

We propose a novel high efficiency (≈40%) generator system capable of providing 1 kWe along with hot water on-demand. The integration of two novel concepts: 1) an internal combustion engine (ICE) operating on Spark-Assisted Compression Ignition (SACI) combustion of natural gas (NG), and 2) a bottoming Organic Rankine Cycle (ORC) with waste energy recovery (WER) from ICE exhaust enables the overa ...

Military personnel must be protected from diseases transmitted by ticks and fleas, including Lyme disease. Effective surveillance of tick and flea vectors is vital to determine the population present, whether they are carrying disease, and whether control campaigns are working. Unfortunately, current surveillance tools are ineffective. In Phase I TDA designed, prototyped, and tested a novel ti ...

Civilian and military organizations throughout the world perform surveillance to combat vector-borne disease. Of particular concern to the U.S. military are mosquito genera Anopheles, Aedes and Culex, which are important vectors for malaria, dengue and West Nile virus respectively, and sand fly genera Phlebotomus and Lutzomyia, both vectors for leishmaniasis. The trap most commonly used for by U.S ...

This proposal contains the description for a hearing protection device (HPD) fit-test instrument, the CCA-200fit. The CCA-200fit has the capability to determine if an individual is receiving effective noise protection from an HPD. The CCA-200fit also has training capabilities via a display, audio, and a touchscreen which will allow it to provide instruction, feedback, and results to the individual ...