Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Universal Microfluidic Device Platform to Enable Real-Time Continuous Measurement of Biomarkers of Coagulopathy Directly in Trauma Victims

    SBC: Aptitude Medical Systems, Inc.            Topic: DHP15012

    Traumatic hemorrhage is the primary mechanism of death in potentially survivable combat injuries, and is the leading cause of death for civilians under the age of 44. Trauma-induced coagulopathy develops quickly, resulting in a hypocoagulable state with increased bleeding, and a 4-fold increase in mortality. The protocolized but blind provision of large volumes of blood products, while beneficial ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  2. Stabilized Antimicrobial Peptides to Combat Multidrug-Resistant Biofilm

    SBC: ALLVIVO VASCULAR, INC.            Topic: DHP15007

    Infections involving multidrug resistant organisms (MDROs) post a substantial threat to military populations. Critical barriers to progress in the treatment of wound infections are the need for therapeutics effective against MDROs and therapeutics effective against biofilms. The goal of this application is to further develop two novel engineered antimicrobial peptides (eCAPs) for treatment of MDRO ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  3. Novel Intraocular Visualization Tools

    SBC: Neuroctix Corp            Topic: DHP15016

    A surgical insert for an 18-gauge needle has been developed incorporating two working channels, one for forward-looking 3D imaging, and a second working channel for a therapeutic embodiment (cutting, coagulation, precision injection of drugs, etc). We propose here an approach to scale down the insert to allow it to be incorporated in smaller gauge (20, 22) needles with significant size, weight and ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  4. Security & Safety Co-Analysis Tool Environment

    SBC: ADVENTIUM ENTERPRISES, LLC            Topic: DHP15004

    Health Delivery Organizations, including the Military Health System, are increasingly using networked medical devices to benefit from improved information accuracy, lowered costs, and improved patient outcomes. These benefits, however, are threatened by the security risks posed by the interactions between the networked devices, and their connection to IT systems which are at risk of cyber attack. ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  5. Rapid Detection of Borrelia burgdorferi (Lyme disease) from Ticks

    SBC: VECTOR TEST SYSTEMS            Topic: DHP15006

    VecTOR Test Systems, Inc will develop assay for rapid detection of the Lyme disease pathogen Borrelia burgdorferi in ticks in a field setting. In Phase I, feasibility of the concept will be determined by developing a prototype assay that has the potential to detect Borrelia burdorferi. The overall objective is to develop product/s that will quickly and accurately determine whether arthropods colle ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  6. Novel Rewarming Technique for Cyropreserved Tissue

    SBC: TDA Research, Inc.            Topic: DHP15014

    TDAs proposes to develop a novel RF heating process for rewarming cryogenically preserved tissues and organs. TDAs approach is to optimize the RF frequency and power, along with the chemical composition, size and morphology of infused nanoparticles so that they heat tissue samples rapidly and uniformly. In this manner, the cryoprotectant solutions pass from the vitrified state to the liquid stat ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  7. Optimization of Cryoprotectants, Cryotherapeutics, and Protocols for Cryopreservation of Large Tissue Systems

    SBC: X-Therma Inc.            Topic: DHP15013

    X-Therma Inc. aims to deliver highly effective, non-toxic cryoprotective agents (CPAs) using unique peptidomimetic polymers which not only mimic the outstanding ice inhibiting effects of naturally occurring antifreeze proteins, but also conquer the cons such as high cost and protease degradation. Widely used biopreservation media contain DMSO above cytotoxic concentrations, an unavoidable concern ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  8. Rapid Detection of Borrelia burgdorferi (Lyme disease) from Ticks

    SBC: NANOCOMPOSIX INC            Topic: DHP15006

    Lyme disease is the most common tick-borne disease in North America and one of the fast-growing infectious diseases in the United States. An inexpensive, portable and accurate diagnostic device for the detection of Borrelia bacteria in the deer tick will be developed. The diagnostic device will consist of an efficient extractor for disrupting the hard exoskeleton on the tick, an ultra-sensitive ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  9. Methodologies and Tools for Securing Medical Device Systems in Integrated Clinical Environments (ICE)

    SBC: HOW MANY ENGINEERS INC            Topic: DHP15004

    Develop an interoperable specification language for the security properties of an ICE supervisor, network controller, logger, and supervisor app components for an interoperable MAP/ICE system architecture that is PNP interoperable, both human and machine readable, defined by a clearly delineated scope and purpose, suitable for both human and automated analysis at assembly time and run time, extens ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  10. Intraoperative Scanning Laser Ophthalmoscope

    SBC: Hedgefog Research Inc.            Topic: DHP15016

    Ocular injuries have constituted approximately 13% of all casualties from Operation Enduring Freedom/Iraqi Freedom. Of 76 patients that sustained open globe injuries and underwent surgery at Walter Reed National Military Medical Center to restore vision, 38% ultimately went blind. In many cases, severely scarred corneas preclude adequately visualizing the retina and other intraocular structures t ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
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