Award Data

To address the U.S. CBD need for novel autoinjector technology that provides the warfighter with a compact, field-ready, cost-effective platform for long-term storage of any given CBT antidote that does not present a significant logistical burden, Physical Optics Corporation (POC) proposes to develop a Microfluidic Pneumatic Autoinjector (MPA) platform. The MPA will provide an innovative universal ...

A prefilled auto-injector device for storing a beneficial agent in a dry and stable format alongside a diluent, and automatically delivering the beneficial agent to a patient after reconstitution. The device comprises an automatic needle insertion mechanism and automatic needle retraction mechanism and is safe and disabled after use. The primary drug container of the auto-injector is made from ...

Oraganophosphorus poisons are potent nerve agents that function by inhibiting the action of acetylcholinestrase in nerve cells. Of these, G-class nerve agents including: Taubin, Soman and Saurin, and, V class agents such as VX represent a significant threat to US military personnel. Human plasma enzyme, Butyrylcholinesterase detoxifies organophosphates by making a covalent bond with them at stoich ...

A novel high-sensitivity biodosimeter technology is proposed that can perform rapid, non-invasive measurement radiation biomarkers in solid human tissues such as fingernails and teeth.

TDA Research, Inc. and the University of Colorado at Boulder will team together to develop a responsive sequestration coating for chemical warfare agents. The coating will be easily applied to surfaces where it will cover and contain chemical warfare agents on vehicles or other hardware known or suspected to be contaminated. A color change of the coating will indicate locations of underlying surf ...

We propose a next-generation reader system for Rapid Diagnostic Tests using lateral flow immunoassay cartridges. The system includes a rugged and lightweight reader that is built on a cellphone platform, a centralized data server, and bio-surveillance application software. The server communicates with readers securely over Internet, cellular and other networks. Reader design aims to provide the ...

A new and promising algorithm is proposed based on hyperspectral unmixing by a sequential processor that will be further developed for data fusion to both enhance sensor sensitivity and eliminate the need for separate background interrogation, thereby allowing for fast real time detection. Sensor sensitivity will be improved by a combination of passive FTIR spectroscopy, and active thermal imagin ...