Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Topic 375: Novel Diagnostic Imaging Modality for Monitoring Tumor Responses to a Hyperthermia Immunotherapy (Moonshot)

    SBC: Imago Systems, Inc.            Topic: NCI

    Immunotherapies have been emerging in the past decades as powerful approaches for cancer treatment. However, the immune system is complex, and therapy efficacy is substantially affected by the tumor microenvironment. For this reason, it is currently difficult to visualize tumor response and predict therapeutic efficacy. In this Contract, Imago Systems, Inc., a company with substantial experience i ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. A system to detect fall occurrence and location in hospital settings

    SBC: BARRON ASSOCIATES, INC.            Topic: NIA

    Fall detectionassessmentand prevention is a challenging issue across the care continuumDespite wide recognition as a considerable problemfall related injuries are still the most frequently reported adverse events in hospital inpatient settingswithof patients falling at least once during their stayAccording to the Agency for Healthcare Research and Quality reportstoof falls result in injuryIn the U ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. GreenCare Interactive Guide for Knee Replacement Surgery

    SBC: PEER Technologies PLLC            Topic: NIA

    Project SummaryAbstract The goal of this Phase I work is to finish development of an innovative interactive app designed to help patients appropriately use total knee replacementTKRsurgery and provide support to achieve best outcomesTKR is highly effective for treating advanced osteoarthritis of the kneebut it has risksAppropriate use can be assured by engaging patients in a Shared Decision Making ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. A Computer Model of Renal Physiology for use as a FDA Medical Device Development Tool

    SBC: HC Simulation, LLC            Topic: FDA

    The purpose of this proposal is to develop a validated physiological model of the human physiologyespecially the cardio renal axisfor submission to the FDA Medical Device Development Tool pilot programThe model will be used to aid in the development and regulation of medical devices designed to treat hypertensionExamples include devices for renal nerve ablationelectrical stimulation of the carotid ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. BT-11: A First-in-class Oral Therapeutic for Inflammatory Bowel Disease

    SBC: Biotherapeutics, Inc.            Topic: NIAID

    BTA First in class Oral Therapeutic for Inflammatory Bowel Disease Biotherapeutics IncBTIdevelops oral first in class therapeutics for autoimmune diseasesBTa lead compound for treating inflammatory bowel diseaseIBDbelongs to a new chemotype and targets the novel Lanthionine Synthetase C LikeLANCLpathwayBTI will file an IND for BTinmonthsSignificanceIBD afflicts overmillion Americans andmillion peo ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Powerful Solid-State Sources to Enable Advanced EPR and DNP-NMR Measurements

    SBC: Virginia Diodes, Inc.            Topic: 400

    VDI Project Summary AbstractThe NIH Division of Cell Biology and Biophysics supports studies of the biological macromolecules that affect the function and structure of living cellsand often play a role in diseaseWithin the realm of biophysicsone of the most important tools to study the structure and interactions of these molecules is nuclear magnetic resonanceNMRFor exampleNMR has been used to stu ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. Development of Non-Stigmatizing Hip Protection for Prevention of Fall-Related Injuries

    SBC: Alba-Technic, LLC            Topic: NIA

    PROJECT SUMMARY ABSTRACT Hip fracture is one of the most serious fall related injuries in older adultshas a high rate of mortality and higher rate of disabilityThe incidence of hip fractures continues to increase as older adults become a larger proportion of the U SpopulationWithin one year post hip injuryof elderly die andof community dwellers are placed in nursing homesAccordinglyhip injury prev ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Development of immunoassays for highly sensitive diagnostic monitoring of traumatic brain injury using novel astroglial injury-defined biomarkers

    SBC: Immunarray USA, Inc.            Topic: 101

    ABSTRACT Traumatic brain injuryTBIis an expanding public health epidemic with complex pathophysiology that is difficult to diagnose and thus treatTBI blood testing should provide simplereliablereal timeobjective diagnostic monitoring and outcome prediction across the entire severity spectrumNeurotrauma biomarkers with insight into underlying TBI processes can address these needsAt UCLADrWanner s t ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Microfluidic CAR-T Cell Processing Device

    SBC: GPB SCIENTIFIC, LLC            Topic: 101

    ABSTRACT The goal of this Fast Track STTR project is to develop a Deterministic Lateral DisplacementDLDmicrofluidic device that can enrich white blood cellsWBCsfrom a typical leukapheresis unit inhrfor use in manufacturing cancer cellular immunotherapyChimeric antigen receptor T cellCAR Ttherapy has been recommended for FDA approval to treat relapsed or refractory pediatric and young adult patient ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Antimicrobial and Biocompatible Endotracheal Tubes

    SBC: Wynnvision LLC            Topic: NHLBI

    Olga ZolotarskayaPhDPI PD Project TitleAntimicrobial and Biocompatible Endotracheal Tubes Abstract Ventilator associated pneumoniaVAPoccurshoursor morefollowing endotracheal intubation and accounts for half of all cases of hospital acquired pneumoniaCDC reports and many clinical studies point to a critical need for preventing ventilator associated infections rather than fighting an often losing ba ...

    SBIR Phase I 2018 Department of Health and Human Services
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