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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. An Integrated Microarray Printing and Detection System

    SBC: BIOSENSING INSTRUMENT, INC.            Topic: 400

    DESCRIPTION provided by applicant Microarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugs Typically protein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another device During each testing cycle the entire microarray becomes expos ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. STTR Phase I: Novel Radar Using 3D Printed Luneburg Lens for Autonomous Transportation

    SBC: Tucson Microwave Innovations LLC            Topic: EW

    The broader impact/commercial potential of this project is significant. The research results will address the resolution and detection speed requirements of autonomous driving in complex environments such as urban scenarios. The next major revolution of transportation is undoubtedly autonomous driving which will bring great potential benefits in terms of safety, mobility and related productivity. ...

    STTR Phase I 2017 National Science Foundation
  3. SBIR Phase I: High multiplex visual mapping of heterogeneity in FFPE biospecimen

    SBC: BioSyntagma, LLC            Topic: BM

    This SBIR Phase I project will address drug resistance in cancer patients through the advanced analysis of biopsies. Not only is each patient unique but their tumor contains a high level of genetic diversity as well. Overlooked diversity within patient tumors can lead to inadequate treatment and consequently acquired drug resistance, and has also been shown to predict therapeutic response to certa ...

    SBIR Phase I 2017 National Science Foundation
  4. SBIR Phase II: Quasi-Active Prosthetic Ankle System: Dynamic Angle and Stiffness Optimizations for Multiple Gait Activities

    SBC: SpringActive, Inc.            Topic: EW

    The broader impact/commercial potential of this project is that the proposed system will enhance the ability of the 1.3 million people currently living in the United States with a lower limb amputation to walk in unconstrained environments. The proposed Quasi-Active Prosthetic Ankle System (QPAS) addresses the RH6: Human Assistive Technologies area. QPAS will be lightweight, have a long battery li ...

    SBIR Phase II 2017 National Science Foundation
  5. Disaggregation of Toxic Protein Oligomers in Brain with Electromagnetic Treatment

    SBC: NEUROEM THERAPEUTICS, INC.            Topic: 104

    ABSTRACT Formation of misfolded protein oligomers in neurons is an early and causative event in a variety of neurodegenerative diseases such as Alzheimer s Disease amyloid and tau oligomers Fronto temporal lobe dementia tau oligomers and Parkinson s Disease synuclein oligomers These toxic oligomers share a common aggregation mechanism that involves formation of hydrogen bonds betwee ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Tools for Accelerating R&D for Historically Understudied Protein Kinases

    SBC: LUCEOME BIOTECHNOLOGIES, LLC            Topic: NCATS

    Protein kinases are central players in almost every aspect of human physiology and serve as critical mediators of signal transduction The dysfunction of many kinases is implicated in cancer diabetes inflammation and cardiovascular diseases and many are validated targets for therapeutic intervention The human genome encodes protein kinases Yet the or so marketed protein kinase drugs ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Application of PPODA-QT for embolization of aneurysms

    SBC: ANEUVAS TECHNOLOGIES, INC.            Topic: 101

    A cerebral aneurysm is an abnormal enlargement or pouch that forms from a weakened vessel segment in the brain Often going unnoticed and untreated an aneurysm can cause a sudden and catastrophic hemorrhage or stroke Approximately of patients die from an aneurysm rupture even before receiving medical attention and of patients die despite medical treatment Patients that survive typical ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Regulators of NaV1.7 Channels: Novel Anti-Allodynic Drug Candidates

    SBC: REGULONIX, LLC            Topic: 102

    PROJECT SUMMARY Chemotherapy induced peripheral neuropathy CIPN is a common prevalence and potentially dose limiting side effect of many cancer chemotherapy drug treatment regimens Clinically CIPN presents with pain that is burning shooting or electric shock like The increase in prevalence of cancer coupled with an increase in the cancer survival rates due to chemotherapy regimens ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Dodecafluoropentane Prevents Ischemia Reperfusion Injury in Contemporary Acute Myocardial Infarction Management

    SBC: NUVOX PHARMA, LLC            Topic: NHLBI

    Due to multiple factors time to administration of lytic therapy or emergent percutaneous coronary intervention PCI in acute ST segment elevation myocardial infarction STEMI may be delayed resulting in loss of additional myocardial tissue These delays are virtually impossible to overcome in remote regions and are associated with increased mor ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Development of the Building Efficacy for Successful Tapering (BEST) Program

    SBC: GOALISTICS, LLC            Topic: NIDA

    ABSTRACT Over million Americans suffer from chronic pain The use of chronic opioid therapy COT for pain has increased dramatically as have reports of opioid misuse abuse dangerous interactions with other drugs overdose and death As concerns over the alarming effects of COT have risen regulatory efforts have increased as well including medically supervised opioid tapering Tapering ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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