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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Wireless withdrawal detection and monitoring system for neonatal abstinence syndrome.

    SBC: REKOVAR INC            Topic: NIDA

    PROJECT SUMMARY Neonatal abstinence syndrome (NAS) is an opioid withdrawal syndrome that develops shortly after birth to in utero-exposed neonates. The cost of NAS is high: newborns with NAS are typically receive care in the Neonatal Intensive Care Unit (NICU), where the daily cost of care is high. Nearly 22,000 infants are born with NAS each year at a cost of $1.5 billion1. Moreover, medication-b ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Variable Leg Length Ground Robot with Novel Prismatic Actuators

    SBC: TRITON SYSTEMS, INC.            Topic: HR001119S003523

    Triton Systems, Inc. will work in collaboration with Professor Mark Yim of the University of Pennsylvania (UPenn) to design a viable, robust ground robot with novel, reconfigurable actuators. This robot can reconfigure from a wheeled state to a legged state, enabling it to overcome tall obstacles and rough terrain. This ground robot will also be of a modular nature, able to be combined with others ...

    STTR Phase I 2020 Department of DefenseDefense Advanced Research Projects Agency
  3. Vaccination against Zika virus infection using mosquito NeSt1 protein

    SBC: L2 DIAGNOSTICS LLC            Topic: NIAID

    Arthropod-borne viruses (arboviruses) present a substantial threat to human and animal health worldwide. They are transmitted by hematophagous arthropods, in which mosquitoes are one of the main transmitters. The mosquito specie, Aedes aegypti, is the primary mosquito vector of several widely spread arboviruses as zika, dengue or West Nile viruses. Mosquitoes transmit these pathogens by inoculatin ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Using Targeted Lipid Nanoparticles to Deliver Chemotherapeutic Agents againstPancreatic Cancer

    SBC: Doric Pharma            Topic: 102

    PROJECT SUMMARY/ABSTRACT Pancreatic cancer continues to be a devastating disease with less than 10% 5-year survival. Pancreatic cancer is aggressive and there are no good tools for early detection. By the time of diagnosis, the tumor is often surgically unresectable. At this stage, patients are often treated with different chemotherapeutic agents or their combination, which while potent, have sign ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Using Mobile Devices for Neurofeedback to Reduce Opioid Use in Chronic Pain

    SBC: CrossComm, Inc.            Topic: NIDA

    Abstract One in five Americans has chronic pain. Many pharmacological pain interventions exist but increase risk of opioid use disorder (OUD). As a result, there is an urgent need for non-addictive pain treatments. One non- addictive pain treatments is neurofeedback, or electroencephalogram (EEG) biofeedback, which trains patients to regulate brain states linked to physiological relaxation. Neurof ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Treatment of diabetic retinopathy with TrkB agonist antibodies

    SBC: ZEBRA BIOLOGICS INC            Topic: NEI

    Project Summary/AbstractDiabetic retinopathy (DR) is a major co-morbidity for patients with Type 1 and Type 2 diabetes. The incidence and severity of DR increase with duration of diabetes and approximately 30 percent will experience vision-threatening deficits. Work over the past decade has shown that the neural deficits observed in DR occur early in the natural history of the disease and likely p ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. The Assessment of Smart Phone Everyday Tasks (ASSET): A new IADL test for early AD

    SBC: ADK Group, LLC            Topic: NIA

    Project SummaryImpairment in instrumental activities of daily living (IADL) is a hallmark of Alzheimer’s disease (AD) dementia and a major source of patient and caregiver burden. Similarly to cognitive changes in AD, subtle difficulties in IADL may begin even before the stage of amnestic mild cognitive impairment (MCI). Recently, greater emphasis has been placed on preclinical AD, which consists ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Sparse Information Orbit Estimation for Proliferated LEO

    SBC: Braxton Technologies, LLC            Topic: HR001119S003522

    Rapidly expanding Low Earth Orbit (LEO) satellite constellations force traditional ground-based tracking methods to adapt as the current ground sensor networks can no longer provide a data rich tracking environment. Accurate tracking information is continually consumed by the Government and private sector to varying degrees of accuracy throughout satellites’ mission lifecycles to provide and uti ...

    STTR Phase I 2020 Department of DefenseDefense Advanced Research Projects Agency
  9. Sorting live cells using RNA-targeting CRISPR-Cas9 (RCas9)

    SBC: DAHLIA BIOSCIENCES, INC.            Topic: 172

    Project Summary/Abstract Transcriptomic-based approaches, and in recent years, single-cell RNA sequencing, are revolutionizing our understanding of cellular heterogeneity, opening up a new route to identify novel cell markers at unprecedented scale across many different cell types. ​RNA-based live-cell sorting opens up andgt;99% of the marker space to enable higher specificity cell sorting. Howe ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  10. SHAPE-BASED GENERALIZATION BOUNDS FOR DEEP LEARNING

    SBC: GEOMETRIC DATA ANALYTICS INC.            Topic: NGA20A001

    We propose to develop a theoretical understanding of the relationship between intrinsic geometric structure in both training and latent data and characteristics of functions learned from that data for deep neural network (DNN) architectures. Along the way we propose to also understand the structure of the neural networks that are best trained on a given data set. Both of these theories will lead t ...

    STTR Phase I 2020 Department of DefenseNational Geospatial-Intelligence Agency
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