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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Aberration-correcting Topologically Optimized Metasurface (ATOM)

    SBC: PHYSICAL SCIENCES INC.            Topic: HR001119S003524

    Metalenses, with their ability to arbitrarily control the amplitude and phase of light across a band of wavelengths, have the potential to disrupt imaging and communication systems which rely on traditional lenses to focus, collimate, and otherwise manipulate optical signals, and are under increasing pressure to operate with reduced size and weight. We propose to design, develop, and demonstrate a ...

    STTR Phase I 2020 Department of DefenseDefense Advanced Research Projects Agency
  2. A Catalytic Filter System for Indoor Air Quality Improvement

    SBC: TDA RESEARCH, INC.            Topic: R

    Project Abstract According to the EPA, indoor levels of pollutants are often 2-5 times and up to 100 times higher than outdoor levels and people spend ~90% of their time indoors. The combination of energy saving methods such as tightly sealed buildings and reduced ventilation rates combined with increased use of synthetic building materials and furnishings, personal care products, pesticides, hous ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  3. A Chatbot Utilizing Machine Learning and Natural Language Processing to Implement the Brief Negotiation Interview to Improve Engagement in Buprenorphine Treatment among Justice-Involved Individuals

    SBC: CENTER FOR PROGRESSIVE RECOVERY LLC            Topic: NIDA

    Project Summary/Abstract This Administrative Supplement proposes the participation of a 3-member team from the Center for Progressive Recovery, LLC (CPR) in the Innovation Corps (I-Corps™), an intensive, 8-week program focused on developing a successful commercialization plan and business model for technology-driven start-ups funded by NIH’s SBIR Phase I mechanism. The program would entail tra ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. A Digital Therapeutic to Advance the Delivery of Effective Interventions for Suicide Prevention

    SBC: OUI THERAPEUTICS INC            Topic: 104

    ABSTRACT Suicide is a top ten cause of death in the US and rates of suicide have increased steadily for the last twenty years. Despite this, there is a paucity of research on treatment programs designed to reduce suicide attempts and none that include a digital therapeutic. In this Phase I SBIR application Oui Therapeutics, LLC proposes a project to: 1) create a beta version of the Oui app (called ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced generation infection-proof anti-HIV CAR-T with YY1 RNAi to block T cell exhaustion in NHP model

    SBC: IT Bio, LLC            Topic: NIAID

    This FastTrack Phase 1/2 application aims to create a new IND-ready CAR-T platform for the treatment of HIV, developed in the laboratory and tested in non-human primates. Molecular engineering techniques have been applied to create chimeric antigen receptors (CAR) expressed in T cells to target HIV-infected cells. CD4-based CARs are designed to achieve immune eradication of HIV1 infections through ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Aerosol immunotherapy for treatment of human metapneumovirus infection

    SBC: MUCOMMUNE, LLC            Topic: NIAID

    Project Summary Human Metapneumovirus (MPV) is the second leading cause of lower respiratory tract infections in infants and young children, and a major cause of respiratory illness in immune compromised adults and the elderly. Unfortunately, there is no effective therapy or vaccine for MPV, and only supportive medical care is available for both pediatric and geriatric MPV patients. We believe a p ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  7. AFFINITY REAGENTS FOR THE IMMUNE SYSTEM OF GUINEA PIGS

    SBC: QOOLABS INC            Topic: 83

    Guinea pigs have been used as experimental animals for centuries. Due to their biological similarities to humans, guinea pigs were used in many fields of biomedical research, such as nutritional research, vaccine research and development, hormonal studies, auditory system studies, and infectious disease studies. The usefulness of guinea pig as a small animal model for biomedical research has been ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  8. A First-in-Class Antibody Therapeutic for Treatment of Acromegaly

    SBC: ELIXERA, INC.            Topic: 200

    Project Summary: Acromegaly is an endocrine disorder caused by a benign pituitary tumor that affects approximately 25,000 adults in the US. Left untreated, the average life expectancy is 10 years from diagnosis. It is characterized by excess skeletal growth, soft-tissue enlargement, and permanent disfigurement, accompanied by metabolic dysfunction resulting from excess growth hormone secreted by t ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  9. A Genes-to-Molecules Platform for Expanding Natural Product Diversity

    SBC: Lassogen, Inc.            Topic: NCCIH

    Project Summary Natural products (NPs) and derivatives thereof provide a rich source of chemical matter for drug discovery and development. Over the past 30 years, NP-derived drugs have accounted for more than 35% of FDA approvals. Despite their demonstrated importance, development of new NPs has slowed over the past 15 years due to the lack of efficient methods for discovery, production, and opti ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  10. A High Power, Broadband 395 GHz Gyrotron Amplifier for DNP-NMR and EPR Spectroscopy

    SBC: BRIDGE 12 TECHNOLOGIES, INC.            Topic: 400

    Project Summary / Abstract We propose to develop a novel gyro traveling wave tube amplifier (gyro-TWT) at 395 GHz with an output power of 500 W and an operating bandwidth exceeding 3 GHz and a small signal gain andgt; 45 dB. The amplifier will be used in Dynamic Nuclear Polarization (DNP) enhanced Nuclear Magnetic Resonance (DNP-NMR) experiments and Electron Paramagnetic Resonance (EPR) experiment ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
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