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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Human Performance Optimization
SBC: REJUVENATE BIO INC Topic: SOCOM17C001Special Operations Forces (SOF) are an integral aspect of the US military. SOF operators are among the most elite and highly qualified individuals in the U.S. military. As such, extraordinary physical and mental demands are placed upon them to excel in extreme environments for extended periods of time. This unrelenting cycle of combat deployments and intense pre-deployment training shortens the fu ...
STTR Phase I 2018 Department of DefenseSpecial Operations Command -
System for Nighttime and Low-Light Face Recognition
SBC: Systems & Technology Research LLC Topic: SOCOM18A001Face recognition performance using deep learning has seen dramatic improvements in recent years. This improvement has been fueled in part by the curation of large labeled training datasets with millions of images of hundreds of thousands of subjects.This results in effective generalization for matching over pose, illumination, expression and age variation, however these datasets have traditionally ...
STTR Phase I 2018 Department of DefenseSpecial Operations Command -
A Method to Increase Buprenorphine Treatment Capacity and Effectiveness
SBC: CBT4CBT LLC Topic: R42The goal of this fast track STTR proposal is to expand buprenorphine maintenance therapy for opioiddependent patientsOvermillion people in the US are addicted to opiatesProviding effective agonist therapymethadone or buprenorphinecoupled with behavioral counseling greatly improves outcomesreduces morbidityand reduces societal costsMethadone maintenance treatment has been limited due to complex sta ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Discovery of Zika virus therapeutics using a replicon assay
SBC: MICROBIOTIX, INC. Topic: RABSTRACT The Zika virusZIKVis the cause of an explosive pandemic of infections across South and Central Americathe Caribbeanand the southeastern region of the United StatesZIKV is a flavivirusa family of small positive strand RNA viruses that includes Dengue virusDENVWest Nile virusWNVYellow fever virusYFVand hepatitis C virusHCVZIKV is transmitted to humans by mosquitoes of the Aedes genusFor the ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Production and Characterization of Human Immunoglobulin Producing Goats for Diagnostic Reagents and Therapeutics
SBC: SAB CAPRA, LLC Topic: NIAIDProject Summary A research plan is proposed to engineer goats that produce fully human immunoglobulinThese animals will be evaluated as a candidate platform system for production of both targeted therapeutic immunoglobulin as well as reagent antibodies for standards and controls of serological assays of human clinical samplesPrevious studies have demonstrated that ungulates such as cattle can prod ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
The Kappa Partial Agonist PPL-103 as a Potential Cocaine Abuse Pharmacotherapy
SBC: PHOENIX PHARMALABS, INC. Topic: NIDAAbstract Currentlyclinically used drug abuse medications exist for treatment of addiction to opiatesalcoholand nicotinebut not cocaineThe objective of the proposed project is to test the hypothesis that the partial kappa agonist PPLcan be effective as a pharmacotherapy for treatment of cocaine abuseBecause of chronic drug induced changes in the kappa opioid receptor systemkappa receptor directed c ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Intravascular molecular-structural NIRF-IVUS imaging of coronary artery disease
SBC: IntraVascular Imaging, Inc. Topic: NHLBIThe goal of this Phase I STTR project is to constructoptimizeand test a clinically viable intravascular near infrared fluorescence intravascular ultrasoundNIRF IVUSimaging catheter for simultaneous molecular and structural diagnosis of coronary artery diseaseCADCAD is a worldwide leading cause of death and disabilityincluding acute myocardial infarctioncongestive heart failureand sudden cardiac de ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Advancing a novel portable detection method for cannabis intoxication
SBC: Brain Solutions, LLC Topic: NIDATBD
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Exploration of Low-Cost Long-Timescale Free Energy Perturbations on FPGAs
SBC: Silicon Insite, Inc. Topic: 400Drug discovery is challenging and expensiveespecially in the phase of lead optimization whichpredicts binding to a targetComputational approaches can add substantial valueComputingrelative binding free energiesRBFEbetween congeneric molecules using molecular dynamicsMDgreatly reduces the search space and considerably improves convergenceThe Silicon TherapeuticsSTXINSITE platform uses an RBFE proto ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
MDCT Quantification of hepatic tumor viability for assessment of cancer therapy
SBC: IQ MEDICAL IMAGING LLC Topic: 102Project SummaryAbstract Tumor imaging quantification is critical for diagnosisstagingand treatment evaluationand multi detector CTMDCTis the clinical imaging modality commonly used for patients diagnosed with hepatic malignancy because of its relatively low cost and wide availabilityConventional tumor quantification using either linear or volumetric measurement has demonstrated significant limitat ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health