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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Mitochondrial Antioxidant Neurodegenerative Therapeutics: XJB-5-131 Derivatives
SBC: SOLANO PHARMACEUTICALS, INC. Topic: NINDSDESCRIPTION (provided by applicant): Oxidative damage to mitochondrial is a major source of toxicity in diseases such as Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HD). Mitochondria are energy powerhouses of the cell, and decline in their function by oxidative damage is a common feature among neurodegenerative diseases. Despite years of effort, however, generic ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
The Allogeneic Heart Stem Cell Trial in Hypoplastic Left Heart Syndrome Patients
SBC: CAPRICOR, INC. Topic: NHLBIDESCRIPTION provided by applicant One of the most complex forms of congenital heart disease hypoplastic left heart syndrome HLHS affects an average of in every newborns with a mortality rate of up to percent during the first year of life The overall goal f our research is to develop safe and effective ways to improve short term and long term survival rates in babies born with HL ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Next-generation HiPIMS for e-CVD, PVD, etch, and precision implantation control for PV Manufacturing
SBC: STARFIRE INDUSTRIES LLC Topic: C5616aThe goal of the U.S. Department of Energy (DOE) Solar Energy Technologies Office (SETO) is to accelerate the development and deployment of solar technology to support an equitable transition to a decarbonized electricity system by 2035 and decarbonized energy sector by 2050. The cost of solar electricity is driven by global economies of scale, materials innovation at the cell level, and disruptive ...
STTR Phase I 2023 Department of Energy -
Solar-thermal production of synthetic flake graphite from natural gas
SBC: SolGrapH Inc. Topic: C5613aThis project aims to advance and commercially translate technology that uses concentrated solar radiation to convert natural gas directly into high-quality graphite and hydrogen. The solar-driven pyrolysis process involves no catalyst and releases zero CO2 as it captures carbon in the form of high-value graphite in a scalable, roll-to-roll (R2R) process. The pyrolysis process also produces a high- ...
STTR Phase I 2023 Department of Energy -
Antivirals Targeting Flavivirus Envelope Proteins
SBC: L2 DIAGNOSTICS LLC Topic: N/ADESCRIPTION (provided by applicant): The overall goal of this project is to develop therapeutic antivirals to treat life-threatening flavivirus infections. Enfuvirtide, a clinically successful peptide HIV fusion inhibitor, is the prototype for a new class of antivirals that inhibit viral envelope protein structural rearrangements essential for viral entry into host cells. In preliminary experiment ...
STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
In toto Handheld Bioagent Detector by Digital Fluidics
SBC: Core MicroSolutions, Inc. Topic: N/ADESCRIPTION (provided by applicant): The design and evaluation of a handheld digital microfluidic (DMF) bioagent analyzer is proposed by Core Microsolutions (CMSS) and University of Michigan Professor K.-D. Lee (College of Pharmacy) for a two year Phase I research period in the NIH Small Business Biodefense Program. This proposed research will integrate: 1) Electrowetting on Dielectric (EWOD) drop ...
STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health -
A Portable PET Insert System for Simultaneous TOF-PET and MR Brain Imaging
SBC: PETcoil, Inc. Topic: 101Project Summary Medical imaging technologies such as magnetic resonance imaging (MRI) and positron emission tomography (PET) have been widely used in studying the underlying mechanisms of mental illnesses and neurological disorders such as brain tumors, Alzheimer’s disease, epilepsy, and depression, etc. However, PET and MRI scans are almost always ordered as separate studies on separate machine ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Whole Brain Nanoscale Preservation Imaging
SBC: Nectome Inc. Topic: 101Abstract Summary Nectome will create technologies to enable whole brain nanoscale preservation and imaging a vital step towards a deep understanding of the mind and of the brainandapos s diseases Current brain processing technologies compromise between whole brain applicability or nanoscale resolution our technologies will achieve both si multaneously Similar to the way that next generation ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Broadly Accessible Technologies for Single-cell Joint Analysis of Transcriptome and Epigenome
SBC: EPIGENOME TECHNOLOGIES, INC Topic: 101AbstractHistone modifications carry rich information of cellular memory and gene regulatory mechanisms. Single cell analysis of histone modification in conjunction with transcriptome could recover this critical layer of cell identity and help to dissect the cellular and molecular composition of complex tissues such as the brain. We recently developed an ultra-high throughput single cell multi-omic ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
Using a novel model of antidepressant efficacy to discover new compounds and personalized treatments.
SBC: PAX NEUROSCIENCE, INC. Topic: 102The World Health Organization estimates that bymajor depressive disorderMDDwill be the most common cause of disabilityworldwideAlthough approximatelyinAmericans will suffer from MDD during their lifetimemany patients with MDD go undiagnosed in primary care settingsandare incorrectly diagnosed with MDDGiven the substantial medicaleconomic and social costs involved with MDDthere is tremendous need f ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health