Award Data

The broader impact of this Small Business Technology Transfer (STTR) Phase I project is to create a drug-discovery platform that will screen quickly and early in the process for candidate therapeutics that can enter the central nervous system (CNS). The goal is to minimize the lengthy and expensive clinical trials that ultimately fail because of their failure to enter the BBB by providing a high a ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to develop a new probe to detect low levels of viral load, such as that causing COVID-19. Rapid and reliable kits are not currently readily available. This project will provide rapid detection of viral material using exsiting cost-effective techniques with fewer detection errors. Being able ...

The broader impact/commerical potential of this Small Business Innovation Research (SBIR) Phase I project will be a potentially significant reduction in medication-related falls, injuries, and deaths, as well as a reduction in fall-related medical costs. The number of older adults dying from falls increased by a factor of three between 2000 and 2016, with increased medication use possibly contribu ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to reduce the morbidity and mortality of patients undergoing surgery. Inadvertent bleeding during surgery represents a critical problem that occurs during all types of procedures on millions of patients around the world. This project will advance a robotic surgical tool system using artific ...

The broader impact/commercial potential of this STTR project is advancing the development of environmentally safe packaging. The global packaging market has been estimated to grow to $980 B in 2022, with lids estimated at $1.4 B in 2020. As 40% of plastic is created for one-time-use, a need exists for innovative packaging. The current petroleum plastic lids are not sustainable nor recycled and the ...

The broader impact/commercial potential of this Small Business Technology Transfer Research (STTR) Phase I project is to optimize and validate a novel medical device for early detection and diagnosis of peripheral neuropathy (PN). PN is damage of nerve fibers, typically starting in the skin and distal limbs and migrating to deeper tissue layers as the disease progresses, and affecting an estimated ...

The broader impacts/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to investigate novel noninvasive methods for detecting and quantifying material in the upper esophagus. Reflux occurs when a bolus of gastric contents flows in reverse from the stomach into the esophagus. Symptoms of reflux can include chronic cough, choking, difficulty breathing or swallo ...

The broader/commercial impact of this Small Business Technology Transfer (STTR) Phase I project is to address age-related cognitive impairments. Neurodegenerative disorders are a rapidly growing public-health concern, with Alzheimer’s disease alone projected to affect 13.8 million Americans by 2050. Alzheimer’s disease patients undergo gradual cognitive decline and during this progression, pat ...

The broader/commercial impact of this STTR Phase 1 project will develop an automated system that significantly increases the speed, reliability, and accuracy of disease severity assessment in ulcerative colitis (UC) patients. This lifelong debilitating disease impacts almost 1 M US patients, and developing effective treatments requires accurate, reliable, and timely scoring. Currently, the FDA-app ...

The broader impact/commercial potential of this project is to reduce the burden of accessing information for the 1.5 million blind people in the United States by making a full page of refreshable braille text and tactile graphics available in a device resembling a tablet computer. This assistive technology will provide increased access to braille and enable blind students to read digitized spatial ...