Award Data

Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

To address the U.S. CBD need for novel autoinjector technology that provides the warfighter with a compact, field-ready, cost-effective platform for long-term storage of any given CBT antidote that does not present a significant logistical burden, Physical Optics Corporation (POC) proposes to develop a Microfluidic Pneumatic Autoinjector (MPA) platform. The MPA will provide an innovative universal ...

Oraganophosphorus poisons are potent nerve agents that function by inhibiting the action of acetylcholinestrase in nerve cells. Of these, G-class nerve agents including: Taubin, Soman and Saurin, and, V class agents such as VX represent a significant threat to US military personnel. Human plasma enzyme, Butyrylcholinesterase detoxifies organophosphates by making a covalent bond with them at stoich ...

A novel high-sensitivity biodosimeter technology is proposed that can perform rapid, non-invasive measurement radiation biomarkers in solid human tissues such as fingernails and teeth.

To achieve high-level strategic goals, DoD elements are investigating the potential of adding autonomy to unmanned assets. An autonomous system must be able to amend its"pre-loaded"plan by rapidly assessing the current situation, examining a number of possible outcomes, initiating a course of action and continuing to reassess its decisions and plan. Currently, data needed for training autonomous m ...

Surface temperatures in atmospheric reentry simulations range from 1500-2300 K, while stagnation temperature on the leading edge of a Mach 6 flight vehicle at 25 km altitude is 1817 K. Sensors that can operate at temperatures well above 1273 K are needed to provide reliable validation data for TPS modeling and design tools.We propose to develop a low-intrusive fiber-optical pyrometer capable of m ...

In previous work for NASA, Ultramet and ARA Ablatives Laboratory developed and demonstrated advanced foam-reinforced carbon/phenolic ablators that offer substantially increased performance under high heat flux conditions and reduced weight relative to conventional ablators. The two-piece structure consisted of an ablative-filled foam front surface backed by Ultramet's previously established a ...

A novel composite material ablative TPS for planetary vehicles that can survive a dual heating exposure is proposed. NextGen's TPS concept is a bi-layer functional composite. The top ablative layer is a two polymer composite layer formed in a conformal shape by infiltrating ablative polymer in a Si based polymeric foam with controlled pore size distribution. This layer is for the aerocapture ...

Planetary rocks, soils, liquids and atmospheric gases are ideal targets for scientists to study the possibility of life existence and the habitability, nature and evolution of planetary systems. Currently, NASA uses different sensing technologies to analyze planetary samples. The use of multiple instruments increases the weight, complexity, power consumption as well as the probability of system ma ...