Award Data

Physical Sciences Inc. (PSI), in collaboration with Wayne State University (WSU), proposes to develop a low-cost blast surrogate testing device that can be used to evaluate next generation personal protective equipment (PPE). Although new material advancements could be used to mitigate the blast wave through improved PPE design, a more advanced test surrogate is needed to inform PPE design decisio ...

Precise detection of biomarkers can stratify the disease progression. A set of gene biomarkers can provide high-resolution specificity of the disease complexity. For example, Cytochrome P450 single nucleotide polymorphism (SNP) genes (such as CYP2D6 and CYP2C19) are linked to the metabolization rate of clinically used drugs (~25%). Detection of these polymorphic genes is essential to assess drug m ...

Physical Sciences Inc. (PSI), in collaboration with the University of Connecticut (UConn) including Dr. Robin Bogner, with expertise in pharmaceutical freeze drying and sustained release for novel pharmaceutical formulations, and Dr. Carolyn Teschke, with expertise in bacteriophage biology, proposes to demonstrate long-term stability of bacteriophages between storage temperatures of -20°C and +45 ...

Tissue repair and wound closure have traditionally been performed using mechanical methods, which while necessary to bring the wound surfaces into apposition and provide sufficient strength to avoid dehiscence, are associated with a variety of downstream effects that can prove deleterious to the ultimate repair. An alternative light-based approach called Photochemical Tissue Bonding (PTB) uses che ...

This work is focused on the development of fabrication technology for large form-factor scintillation crystals for multi-modal detection of radioactive sources, and development of mobile imaging and mapping instruments based on these large format scintillators.

Physical Sciences Inc. (PSI), in collaboration with Wayne State University (WSU), proposes to develop a low cost blast surrogate testing device that can be used to evaluate next generation personal protective equipment (PPE). New material advancements could be used to mitigate the blast wave through improved PPE design, but a more advanced test surrogate is needed to inform PPE design decisions. Â ...

Multiple orthotics and prosthetics users would benefit from sensors that can collect physiological information from the user and transmit it wirelessly to the prosthesis. For example, prosthetic sockets have long been one of the primary sources of complaints for both upper- and lower-limb amputees. However, if a user decides to utilize osseointegration in place of wearing a socket, there would no ...

Tissue repair and wound closure have traditionally been performed using mechanical methods, which while necessary to bring the wound surfaces into apposition and provide sufficient strength to avoid dehiscence, are associated with a variety of downstream effects that can prove deleterious to the ultimate repair.  An alternative light-based approach called Photochemical Tissue Bonding (PTB) uses c ...

Physical Sciences Inc. (PSI), in collaboration with the University of Connecticut (UConn) including Dr. Robin Bogner, with expertise in pharmaceutical freeze drying, and Dr. Carolyn Teschke, with expertise in bacteriophage biology, proposes to develop a formulation and process for lyophilization, or freeze drying, of bacteriophages for improved stability to enable bacteriophage treatments in auste ...

This program seeks to develop ultrafast, radiation hard, and rugged scintillators for nuclear battlefields based on high  melting-point temperatures oxide crystal. Doping, co-doping, and alloying schemes will be explored to reach the target of < 5ns decay time, light yield >1000 ph/MeV, moderate energy resolution