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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Extended half-life GlyTR1 combined with checkpoint blockade for Cancer Immunotherapy
SBC: GLYTR THERAPEUTICS, INC. Topic: 102AbstractTreatment of non-resectable recurrent/metastatic solid cancers is currently palliative only and there is an urgent unmet need for novel mechanisms of action and additional paradigm shifting therapeutic options. Antigen- targeting cancer immunotherapies such as bi-specific antibodies (eg Bi-specific T cell engager or BiTE’s) provide a unique approach for cancer immunotherapy. However, app ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Point of Care HPV 16/18/45 DNA Test for Cervical Cancer
SBC: CROSSLIFE TECHNOLOGIES INC. Topic: 102Point of Care HPV 16/18/45 DNA Test for Cervical Cancer. CrossLife Technologies Inc. Project Summary/Abstract Human cervical cancer is the fourth most common cancer among women worldwide [1]. Despite cervical cancer has been thoroughly studied and the mortality has been significantly reduced through efficient screening, these preventive programs are found to be less effective in developing countri ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Quantifying microstructural changes in Alzheimer's disease using Restriction Spectrum Imaging
SBC: Cortechs Labs, Inc. Topic: NIAProject Summary/Abstract The overall goal of this project is to deliver an automated diffusion image analysis tool to be used in a clinical setting that quickly evaluates the diffusion images in conjunction with MR volumetric images and reports diffusion-based microstructural parameters derived from segmented anatomical locations to determine Alzheimer’s disease status of patients. Alzheimer’s ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Developing a novel system combining cognitive assessment with PASCALL FDA-cleared intraoperative anesthesia EEG brain monitor to prevent postoperative neurocognitive disorders in aging patients
SBC: PASCALL Systems, Incorporated Topic: NIAEach day, more than 100,000 patients undergo general anesthesia in the United States. The current practice of general anesthesia is prone to over-sedating patients, either due to the lack of brain monitoring or using brain monitors with inaccurate indices. Over-sedation (at 28% incidence) contributes to perioperative neurocognitive disorders (PNDs) in elderly population (≥65yrs). The cost of PND ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
The Commercialization of High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic Pain
SBC: MICRO-LEADS INC Topic: NINDSAbstract DESCRIPTION. Our FastTrack SBIR proposal has developed HD64—a high-resolution, spinal cord stimulation therapy to provide more pain relief with greater specificity for those suffering from chronic neuropathic pain and opioid dependence. Over 25 million in the U.S. suffer from debilitating pain in the trunk and extremities and 55% depend on opioids to ease their suffering. Opioid abuse h ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Quantitative Modeling Software with Applications to Medical Decision Making
SBC: Berkeley Madonna, Inc. Topic: NLMProject Summary/Abstract In recent years, health care systems and physicians have made concerted efforts to practice evidence-based medicine and provide patients with the best available information when making choices about their medical care. However, medical decisions are often complex with many uncertainties and potential outcomes to consider, some beneficial and some adverse. A popular analyti ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Next generation MEMS-VCSEL technology for ultra-low-cost dental and periodontal swept source optical coherence tomography imaging
SBC: PRAEVIUM RESEARCH INC Topic: NIDCRThis proposal aims to enable a new generation of high-speed, low-cost, wavelength-flexible swept source optical coherence tomography (SS-OCT) imaging device technology targeting applications in dental imaging and based on microelectromechanical systems vertical cavity surface emitting lasers (MEMS-VCSELs) and planar lightwave circuits (PLCs). MEMS-VCSELs provide an unmatched combination of high an ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Leveraging remote blood pressure monitoring and interpretable machine learning to improve clinical workflows for hypertensive disorders of pregnancy
SBC: DELFINA CARE INC. Topic: NICHDProject Summary/Abstract: Hypertensive disorders of pregnancy (HDP) are a leading cause of pregnancy-related deaths in the United States. Specific interventions, such as nutrition counseling and prophylactic aspirin use, are known to prevent the onset and exacerbation of HDP. However, current approaches to identify patients early in pregnancy are limited due to challenges collating patient data fr ...
SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Commercial Readiness in CTS Pain Management
SBC: HIGHLAND INSTRUMENTS INC Topic: NIAMSProprietary: This proposal includes trade secrets and other proprietary or confidential information of Highland Instruments and is being provided for use by the National Institutes of Health (NIH) for the sole purpose of evaluating this SBIR proposal. No other rights are conferred. This proposal and the trade secrets and other proprietary or confidential information contained herein shall further ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Advancing precision pain medicines to the clinic
SBC: NAVEGA THERAPEUTICS, INC. Topic: 104Abstract Chronic pain is pain that persists past the normal time of healing. 1.5 billion people worldwide suffer from chronic pain and this number continues to increase as the elderly population grows, the prevalence of diabetes rises, and cancer survival rates improve. Chronic pain not only severely impacts daily quality of life for many patients, it also places a heavy socioeconomic burden on so ...
SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health