Award Data

On this effort Toyon Research Corp. and The Pennsylvania State University are developing deep learning-based algorithms for object recognition and new class discovery in look-down infrared (IR) imagery. Our approach involves the development of a hybrid classifier that exploits both transfer learning and semi-supervised paradigms in order to maintain good generalization accuracy, especially when li ...

Signature Research, Inc. (SGR) and Michigan Technological University (MTU) propose a Phase I STTR effort to develop a learning algorithm which exploits the spatio-spectral characteristics inherent within IR imagery and motion imagery.Our archive of modelled and labeled data sets will allow our team to thoroughly capture the variable elements that will drive machine learning performance.The overall ...

Modern quantum information systems employ optical photons for long distance communication, operating at ambient temperature, between microwave cavities, which house microwave photons used in quantum computing and microwave detection. These optical photons, carried by fiber-optic or free-space links, offer a low-cost, uncooled alternative to bulky, expensive microwave coaxial cables, which are loss ...

For economically viable large-scale production of microalgae based food and biofuel to become a reality, significant improvements in algal productivity need to be achieved. With current regulatory guidelines, large scale outdoor cultivation of microalgae for these products restricts the use of transgenic algal strains, which in the laboratory, have thus far been the primary strategy taken to effec ...

The discovery of large shale gas reserves in recent years has resulted in the reduction of natural gas price and a need to develop new applications for the available resource. Upgrading shale gas to liquid fuels which are more easily transportable and have greater economic value can result in significant benefits to the US. Coupled with this challenging problem the DOE has a goal of further develo ...

The power output of the high power lasers used in physics research is limited by the materials available for making the gain media in the laser. Future increases in power will require new and better materials. Operation at high power creates great thermal stresses that can lead to effects such as birefringence, thermal lensing or even physical fracture damage to the host itself. Effective cooling ...

To advance a strong and economical biofuels and bioproducts industry, tools are needed for breeding microalgae to improve phenotypes of commercial interest, including biomass yield, culture stability, harvestability, and accumulation of valuable compounds. This project aims to increase biomass feedstock yields by the phototrophic green alga Scenedesmus obliquus by using classical breeding approach ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

The development of radiation detection materials would benefit with greater access to computational models that relate physical traits seen in manufacture with complex energy transitions occurring in the material that control operating performance. However, the HPC requirements behind these models remain beyond the reach of most businesses involved in this small yet vital field impacting National ...