Award Data

This Small Business Technology Transfer Phase I project will involve the development of an innovative spectral image system to track rock material flows through mining operations. Accurately tracking material flows will allow smarter mineral processing circuits and optimized blasting, significantly reducing waste and energy. This addresses two of the central environmental impacts associated with m ...

This Small Business Technology Transfer (STTR) Phase I project aims to apply computational protein design (CPD) to engineer polysaccharide monooxygenases (PMOs) for improved thermostability, so that a cocktail of PMOs and key cellulases will more efficiently convert lignocellulolosic biomass to fermentable sugars. The objectives of Phase I are to: (a) evaluate several natural PMOs for expression, ...

This Small Technology Transfer Research (STTR) Phase I project seeks to develop an alternate aquafeed that does not rely on the inclusion of captured, oceanic forage fish such as menhaden and sardines for its omega-3 content and is suitable for culturing marine fish in land-based recirculating aquaculture systems (RASs). Specifically, six alternate fish feeds will be formulated, pelletized and fed ...

This Small Business Technology Transfer Phase I project is titled ?Performance Optimization Toolbox for Wave Energy Conversion Devices?. Advanced wave prediction and concurrent online adjustment of the operating parameters (such as hydraulic system pressure and generator load) of existing wave energy conversion (WEC) devices have the potential to increase their power extraction efficiency by at le ...

This Small Business Innovation Research (SBIR) Phase I project is aimed at demonstrating commercial viability for a new self-healing corrosion-protection system. Corrosion significantly impacts both the costs and availability of commercial aircraft, costing tens of billions of dollars annually. The proposed Self-Healing Anti-Corrosion Coating (SHAC) is capable of repeatable repair and sustained pr ...

This Small Business Technology Transfer (STTR) Phase I project proposes to engineer butanol tolerance in the yeast Saccharomyces cerevisiae using a novel combinatorial genetic technology designed to enable yield enhancements in microbial production organisms. Microbial production of renewable fuels and chemicals is rapidly expanding. However, toxic products or by-products and engrained metabolic f ...

This Small Business Technology Transfer (STTR) Phase I project proposes to combine a novel metabolically engineered Chinese hamster ovary (CHO) cell line with a unique, high performance, continuous cell-culture bioreactor to demonstrate the commercial viability of producing a bioengineered heparin from CHO cells. This CHO cell line overexpresses critical enzymes in the heparin biosynthesis pathway ...

This Small Business Technology Transfer (STTR) Phase I project is to develop an inexpensive and rapid sensing technology for detection of tuberculosis (TB) at the point of care (POC). Rapid screening of TB in rural areas is difficult because current diagnostic methods are expensive, time consuming (several days to weeks), and require specialized equipment (laboratories and hospitals) that are not ...

This Small Business Technology Transfer (STTR) Phase I Project aims to optimize and test prototypes of continuous, multi-analyte sensors based on stimuli-responsive hydrogels. The proposed sensor array will be capable of monitoring multiple biomarkers relevant to several common human diseases such as diabetes, ketoacidosis, chronic obstructive pulmonary disease (COPD) and even obesity. During this ...

This Small Business Technology Transfer (STTR) Phase I project proposes to establish cost effective methodologies for the efficient production of catechins utilizing a microbial fermentation approach. Preliminary work on the biosynthesis of the catechins, using metabolically engineered Escherichia coli recombinant strains from their flavanone and phenylpropanoid acid precursors, has demonstrated f ...