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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)

    SBC: ECHELON BIOSCIENCES, INC.            Topic: CBD192007

    Organophosphorus (OP) toxins and chemical warfare agents (CWA) are active nerve agents posing significant hazard for both soldiers and civilians. Butyrylcholinesterase (BChE) is a safe and effective bioscavenger that detoxifies OP and CWAs when injected either prophylactically or post-exposure; but a major technical problem has been producing a recombinant form of BChE with acceptable properties f ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  2. Optimized Platforms for Proper Glycosylation and Sialylation of Recombinant Human Butyrylcholinesterase (rBChE)

    SBC: Technology Holding, LLC            Topic: CBD192007

    The threat of organophosphate (OP) chemical warfare agents (CWA) to United States military personnel is a persistent problem due to the relative ease of manufacturing chemical threats compared to nuclear and biological agents. Human butyrylcholinesterase (BChE) has been identified as a probable bio-scavenger of OP CWAs that could be used to protect individuals that could be exposed to OP CWAs. The ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  3. Non-Invasive Monitoring of Changes in Intracranial Pressure Due to Infections in the Central Nervous System

    SBC: Fenix Research Corporation            Topic: CBD192005

    Infections of the central nervous system (CNS) are associated with brain swelling and increased cerebral blood volume, as well as focal cerebral perfusion deficits, variable levels of cerebral blood flow and cerebral vasculitis. The net result is increased intracranial pressure (ICP) along with significant risk of brain tissue herniation and ischemic syndromes. ICP monitoring is critical in the ma ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  4. Development of Small Molecule Therapeutics for Emerging Viral Agents

    SBC: Arisan Therapeutics, Inc.            Topic: CBD192006

    Ebolavirus species including Zaire (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) are responsible for severe hemorrhagic fever outbreaks with high case fatalities in Africa. Weaponized pathogens present an additional threat to the health protection of the warfighter and first-generation prophylactic and therapeutic medical countermeasures (MCMs) may prove inadequate in biodefense settings. Ebolaviruse ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  5. Self-contained Equipment Decontamination System (SCEDS)

    SBC: Integrated Solutions for Systems, Inc.            Topic: CBD192002

    The processes and systems required to decontaminate personnel have received much attention and several effective systems exist. However, decontamination of sensitive equipment, without damage or performance degradation, is a significantly different problem that has not been adequately solved. The wide variety of electronics, fabrics and structural materials together with the infinite variations in ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  6. Development of a Non-invasive Negative Ophthalmodynamometer Capable of Measuring Intracranial Pressure in Humans

    SBC: Equinox Ophthalmic, Inc.            Topic: CBD192005

    Measurement of intracranial pressure (ICP) is essential in the diagnosis and management of numerous life threatening conditions. All current methods used clinically to measure ICP are invasive and require direct access to the cerebrospinal fluid giving them a significant side effect profile. The ability to measure ICP non-invasively would be a major milestone for patients. Spontaneous venous pulsa ...

    SBIR Phase I 2020 Department of DefenseOffice for Chemical and Biological Defense
  7. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications

    SBC: GENECAPTURE            Topic: CBD15C001

    The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

    STTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  8. Novel Approaches to Fully Digital Optical Solutions

    SBC: TOYON RESEARCH CORPORATION            Topic: SOCOM15003

    Digital optical solutions currently have inherent latency due to the processing chain from optical capture with a lens to a display. While system latency in excess of 5 milliseconds is acceptable in most applications where an operator is seated, this threshold is too high for the TALOS application. Being able to move dynamically while processing a digital image of the environment will require a ...

    SBIR Phase I 2015 Department of DefenseSpecial Operations Command
  9. Reduced Size, Weight, and Power, Enhanced Range Electro-Optical and Infrared Sensor Suites

    SBC: TOYON RESEARCH CORPORATION            Topic: SOCOM15004

    The size, weight, and power (SWaP) of mission systems on fixed-wing Intelligence, Surveillance and Reconnaissance (ISR) platforms directly impacts the range and endurance of those platforms. Likewise, miniaturized components in a given system enable increased mission flexibility through more capabilities for a given SWaP. One solution to increase range and enhance resolution on ISR platforms is ...

    SBIR Phase I 2015 Department of DefenseSpecial Operations Command
  10. Night/Day-Enabled Miniature Emplaced Sensor and Infrared Surveillance System

    SBC: Physical Optics Corporation            Topic: SOCOM15006

    To address the USSOCOM need for Team Day/Night Motion Sensors, Physical Optics Corporation (POC) proposes to develop a new Night/Day-Enabled Miniature Emplaced Sensor and Infrared Surveillance (NEMESIS) system, based on the novel use of multi-aperture, compound-eye motion detectors to cue the capture of thermal surveillance imagery. Specifically, the innovation in the compound-eye optical design a ...

    SBIR Phase I 2015 Department of DefenseSpecial Operations Command
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