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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Marburg Virus Prophylactic Medical Countermeasure

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: CBD18A002

    There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  2. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD Research Corporation            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. System for Nighttime and Low-Light Face Recognition

    SBC: Polaris Sensor Technologies, Inc.            Topic: SOCOM18A001

    The objective of this proposal is to develop instrumentation and algorithms for acquiring facial features for facial recognition in low- and no-light conditions.We will use cross-spectrum matching by exploiting infrared polarimetric imagery which tends to show features that match more closely visible imagery than conventional infrared.In addition to thermal infrared, we will also test subjects in ...

    STTR Phase I 2018 Department of DefenseSpecial Operations Command
  4. Human Performance Optimization: Ketone Esters for Optimization of Operator Performance in Hypoxia

    SBC: HVMN Inc.            Topic: SOCOM17C001

    In the setting of altitude-induced hypoxia, operator cognitive capacity degrades and can compromise both individual and team performance. This degradation is linked to falling brain energy (ATP) levels and an increased reliance on anaerobic energy production from glucose. Ketone bodies are the evolutionary alternative substrate to glucose for brain metabolic requirements; previous studies have sho ...

    STTR Phase I 2018 Department of DefenseSpecial Operations Command
  5. Marburg Virus Prophylactic Medical Countermeasure

    SBC: Flow Pharma, Inc.            Topic: CBD18A002

    Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  6. Prediction of Plume Induced Rock Fracture for Landers

    SBC: CFD Research Corporation            Topic: T9

    The landing surface damage and liberation of debris particles caused by rocket plume impingement flow during spacecraft propulsive landing on unprepared surfaces of Moon, Mars, and other celestial bodies poses a high risk for robotic and human exploration activities. Simply determining whether the plume induced loads exceed the bedrock bearing capacity threshold is not sufficient. An integrated m ...

    STTR Phase I 2018 National Aeronautics and Space Administration
  7. Bifunctional Regenerative Electrochemical Air Transformation for Human Environments

    SBC: Skyre, Inc.            Topic: T6

    The proposed Bifunctional Regenerative Electrochemical Air Transformation for Human Environments (BREATHE) for life support and habitation is part of the atmosphere revitalization equipment necessary to provide and maintain a livable environment within the pressurized cabin of crewed spacecraft. Sustainable Innovations (SI) has developed a novel solid state technology for gas compression based on ...

    STTR Phase I 2018 National Aeronautics and Space Administration
  8. Refractory Additively Manufactured Affordable Launch Vehicle RCS

    SBC: Valley Tech Systems, Inc.            Topic: T1

    Due to the rapid maturity of small satellite technologies to meet near term commercial, science and military space applications there is a driving need for development of increased affordable space launch system capability. To address this need, Valley Tech Systems and the University of Texas El Paso (UTEP) is proposing evolving our innovative Affordable Launch Vehicle Reaction Control System (AL ...

    STTR Phase I 2018 National Aeronautics and Space Administration
  9. A Scalable Gas-Particle Flow Simulation Tool for Lander Plume-Surface Interaction and Debris Prediction

    SBC: CFD Research Corporation            Topic: T9

    Spacecraft propulsive landings on unprepared regolith present in extra-terrestrial environments pose a high risk for space exploration missions. Plume/regolith interaction results in (1) the liberation of dust and debris particles that may collide with the landing vehicle and (2) craters whose shape itself can influence vehicle dynamics. To investigate such gas-granular interactions for large-scal ...

    STTR Phase I 2018 National Aeronautics and Space Administration
  10. Intelligent, Autonomous, Distributed Vehicle and Electrical Power System Management

    SBC: Stottler Henke Associates, Inc.            Topic: T3

    The proposed innovation, a distributed architecture for intelligent characterization, fault detection/diagnosis/ reconfiguration/replanning/rescheduling, and adaptive execution, substantially leverages large previous NASA investments to assemble the correct set of technologies to implement all aspects of the required intelligent, autonomous vehicle and distributed EPS and other subsystem managers. ...

    STTR Phase I 2018 National Aeronautics and Space Administration
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