Award Data

To address the SOCOM need for field-operable computing"bricks", Physical Optics Corporation (POC) proposes to develop High-performance Arbitrated LOgic processing Topology (HARLOT) device. HARLOT is a computing brick housed in a man-portable, ruggedized package designed for field use and offers>16 Terabyte non-volatile memory and>1 TeraFLOPS computational capability while consuming

UtopiaCompression and team put forth a novel solution for medical diagnostics and continuous monitoring of combat casualties in the battlefield to improve survivability while reducing cost to the military. We propose advances in both physiological diagnostic intelligence and associated physiological sensors systems for a complete solution. The system will consist of the state of the art physiologi ...

This program will consist of a three prong approach to provide an unbiased assessment and development of subsonic ammunition with the highest success rate balanced against technological advancement. Our feasibility study will include: 1) A brass case utilizing a polymer insert to optimize subsonic interior ballistics, 2) A lightweight low cost aluminum cartridge case utilizing a polymer insert, ...

A new and promising algorithm is proposed based on hyperspectral unmixing by a sequential processor that will be further developed for data fusion to both enhance sensor sensitivity and eliminate the need for separate background interrogation, thereby allowing for fast real time detection. Sensor sensitivity will be improved by a combination of passive FTIR spectroscopy, and active thermal imagin ...

We propose a next-generation reader system for Rapid Diagnostic Tests using lateral flow immunoassay cartridges. The system includes a rugged and lightweight reader that is built on a cellphone platform, a centralized data server, and bio-surveillance application software. The server communicates with readers securely over Internet, cellular and other networks. Reader design aims to provide the ...

To address the U.S. CBD need for novel autoinjector technology that provides the warfighter with a compact, field-ready, cost-effective platform for long-term storage of any given CBT antidote that does not present a significant logistical burden, Physical Optics Corporation (POC) proposes to develop a Microfluidic Pneumatic Autoinjector (MPA) platform. The MPA will provide an innovative universal ...

Neurotoxic organophosphorus (OP) agents (e.g. sarin, soman, VX and tabun) were developed initially as pesticides and adapted for chemical warfare. OP agents are fast acting and lethal at even very low doses. Countering the threat of intoxication by OP nerve agents is an important mission for homeland security. Currently, the most promising strategy to counter OP intoxication is to scavenge the age ...

Oraganophosphorus poisons are potent nerve agents that function by inhibiting the action of acetylcholinestrase in nerve cells. Of these, G-class nerve agents including: Taubin, Soman and Saurin, and, V class agents such as VX represent a significant threat to US military personnel. Human plasma enzyme, Butyrylcholinesterase detoxifies organophosphates by making a covalent bond with them at stoich ...

A novel high-sensitivity biodosimeter technology is proposed that can perform rapid, non-invasive measurement radiation biomarkers in solid human tissues such as fingernails and teeth.

Though vast improvements have been made in various protein expression platforms, limitations arise in the implementation of current purification methods. Traditional chromatographic methods are time intensive, carry heavy material costs, and are difficult to scale - reducing the benefits achieved in protein expression. Affinity-binding methods are promising for scale-up and swiftness of purificati ...