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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Whole Ovary Vitrification for Fertility Preservation

    SBC: 21st Century Medicine, Inc.            Topic: NICHD

    The long term goal of this proposal is to develop a safeeffective and user friendly vitrification system for cryopreservation of whole human ovariesIn the U Sovergirls and women ageare diagnosed with cancer annuallyWhile improved diagnosis and treatment have led to increased survival ratesin premenopausal andin childhood cancer patientsdevastating side effects of cancer therapies include premature ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Improved Amputee Quality of Life Enabled by Tailored, Self-Regenerating Energy Storage Device For Powered Prosthetics

    SBC: GINER INC            Topic: NICHD

    PROJECT SUMMARY Improved Amputee Quality of Life Enabled by TailoredSelf Regenerating Energy Storage Device forPowered Prosthetics Poweredmotorized prosthetics enable users to more naturally perform taskssuch as climbing stairs or rising from a seated positionHowever because the power requirements fluctuate during the gait cyclethe current battery system is not energy efficient and also since ener ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. A Noninvasive Platform to Assess Maternal Risk for Perinatal Complications in the First Trimester

    SBC: Cradle Genomics, Inc.            Topic: NICHD

    Limited information is available about early human placentation when many pregnancy pathologies originateTo address this knowledge gap and begin development of robust diagnostic tool to manage pregnancy complicationswe propose a pilot study based on a highly sensitive immune assay and our company s base technologyTrophoblast Retrieval and Isolation from the CervixTRICTRIC uses a Pap smearconsidere ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. An oral ROCK2-selective inhibitor for treatment of chronic spinal cord injury

    SBC: BIOAXONE BIOSCIENCES, INC.            Topic: 103

    Roughlypeople in the United States will suffer a spinal cord injurySCIthis yearFor the vast majority of themthe injury will leave them incapable of walking orif they have suffered a cervical SCIentirely dependent upon others for assistance in all of their activities of daily living from feeding to personal careMore importantlychances of improvement as a result of therapeutic interventions are blea ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. SkillTalk: Communication Training around Sexual Health Topics for Parents of Youth with Autism Spectrum Disorder

    SBC: DFUSION INC.            Topic: NICHD

    ABSTRACT SkillTalkCommunication Training around Sexual Health Topics for Parents of Youth with Autism Spectrum Disorder Adolescents with Autism Spectrum DisorderASDface a range of impairments in social interaction and communication settingsincluding those involved with sexual communication and behaviorLike their neurotypical peersadolescents with ASD need comprehensive sexual education to learn an ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A Smart Entry Needle System for Peritoneal Access and Insufflation during Laparoscopic Surgery

    SBC: Theranova LLC            Topic: NICHD

    AbstractIn themillion laparoscopic surgeries performed annually worldwideachieving peritoneal access for insufflation accounts for one third of the associated complicationsPeritoneal access is typically achieved using the Veress needleHoweverthe use of the Veress needle has been identified as the source ofof the complications associated with laparoscopic proceduresIt has been shown that complicati ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Ninja Theranostics for overcoming the drug delivery barriers to pediatric brain tumor

    SBC: THERANOSTEC INC            Topic: NICHD

    Ninja Theranostics for overcoming the drug delivery barriers to pediatric brain tumor Project Summary Abstract Pediatric brain tumorsPBTsare the leading cause of cancer related morbidity and mortality among childrenVincristineVCRhas been approved to treat PBTsbut its inability to cross blood brain barrierBBBblood brain tumor barriersBBTBand dose limiting neuropathy have greatly limited its clinica ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Administrative Supplement to restore fee funds

    SBC: AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC.            Topic: NINDS

    Project Summary Traumatic brain injuryTBIcauses detrimental behavioral dysfunctions and brain neurodegeneration butunfortunatelythere currently is no effective pharmaceutical TBI treatmentThe underlying PhaseSTTR grant is to develop a new class of TBI drugs that inhibit the protease cathepsin BGenetically deleting the cathepsin B gene in mice results in substantial behavioral and pathology improve ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. A therapeutic approach for potential prevention of aromatase inhibitor-induced bone loss

    SBC: NANOMEDIC INC            Topic: NIA

    AbstractIn this SBIR Phase I applicationour goal is to demonstrate proof of concept of our lead chelating agent as a potential therapeutic for the prevention of osteoporosis induced by aromatase inhibitorAItherapy in postmenopausal women with hormone receptor positive breast cancerAlthough AI therapy shows great improvements in cancer free and overall survivalits treated patients face a risk of os ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Senescence After Growth Arrest a new therapeutic modality for progeria

    SBC: Atropos Therapeutics, Inc.            Topic: NIA

    Abstract The long term goal of Atropos Therapeutics Incis development of a therapeutic drug for progeria and other aging related disorders based on their ability to regulate the senescence processAt the end of PhaseSBIRwe anticipate having two to five scaffolds that have utility slowing or preventing cellular senescence in tissue cultureIn phasewe anticipate moving scaffolds toward lead selectiont ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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