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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Ab-Initio Geometry Optimization of Large Molecules

    SBC: Q-CHEM INC            Topic: N/A

    DESCRIPTION (provided by applicant): While density-functional calculations of the energy are now feasible for biomolecules, the use of density-functional geometry optimizers is still confined to relatively small molecules containing no more than thirty atoms. The key limitation of conventional density-functional geometry optimizers is that the cost of the geometry optimization scales at least qua ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  2. ABSORBED DOSE MEASURMENTS USING POLYMER/GEL CHAMBERS

    SBC: MGS RESEARCH INCORPORATED            Topic: N/A

    N/A

    SBIR Phase I 1998 Department of Health and Human Services
  3. Access to distributed de-identified imaging data

    SBC: Hx Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The widespread adoption of picture archiving and communications systems (PACS) in radiology and the implementation and deployment of the DICOM communication standard represent an opportunity to link multiple PACS at multiple sites into a distributed data warehouse of great potential utility for investigators in oncology research and epidemiology. Where the f ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  4. A cell-free system for assaying ion channel function

    SBC: INTEGRAL MOLECULAR INC            Topic: N/A

    DESCRIPTION (provided by applicant): Ion channels function as signaling intermediaries that are involved in nerve signal propagation, muscle contraction, cardiopulmonary regulation, and cell metabolism. Their importance is underscored by the existence of dozens of ion channel-specific drugs that treat important neurological and cardiovascular diseases. Despite their importance in human health, ion ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. ACTIVE MIXING MEMBRANE OXYGENATOR (AMMO)

    SBC: Cardiopulmary Technologies,            Topic: N/A

    N/A

    SBIR Phase I 1998 Department of Health and Human Services
  6. Adherence to Antiretrovirals in People Living with HIV

    SBC: NOTABOOK PUBLISHING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): People living with HIV or AIDS (PLWHA) are often prescribed an antiretroviral regimen to decrease risk for opportunistic infection. These multi-medication regimens are highly complex and burdensome and require almost perfect adherence. Consequently, poor antiretroviral adherence is a vexing problem. We propose an engaging, literacy- and motivationally tailored ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  7. Adult Optical Non-Invasive Brain Oxygenation Monitor

    SBC: CAS MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a need for a non-invasive and continuous bedside monitor for brain oxygenation for adult human patients. Near-infrared spectroscopy (NIRS) is an optically based technique that could meet such demand. However, NIRS instruments have yet to achieve their initially expected potential of becoming routine clinical monitors complementary to pulse oximetry. ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Affordable large population genomic DNA collections

    SBC: MOLECULAR STAGING, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The availability of large human genomic DNA sets of known ethnic origin remains a persistent problem for epidemiology and disease gene research. In this grant two valuable resources are combined to solve DNA availability problems. Molecular Staging Inc (MSI) has developed a technology, termed Multiple Displacement Amplification (MDA), that is capable of produci ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Aging Resistant Ceramics for Total Hip Arthroplasty

    SBC: SINTX TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Zirconia bio-ceramics (e.g. Prozyr) have the highest toughness and strength compared to other bio-ceramics such as alumina (e.g. Biolox) or zirconia-toughened alumina (Biolox-Delta). However, as highlighted by the recent recall of St. Gobain zirconia heads, a critical need remains to develop bio-ceramics with both significantly reduced wear characteristics and ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  10. A High Resolution X-ray Fluorescence Detector

    SBC: HD TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): It has been repeatedly emphasized in the BioSync Report that the development of better XAS detector systems is critical in solving the problem of detectors lagging behind synchrotron sources. The detector bottleneck encountered is in two areas: one is detector count rate limitation, and the other is its limited rejection rate of background in order to examin ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
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