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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Cell therapy of diabetes using broad spectrum multipotent stem cells
SBC: PLUREON CORP. Topic: N/ADESCRIPTION (provided by applicant): Transplantation of insulin-producing cells in many diabetes patients potentially would restore normal glucose homeostasis and prevent the severe long-term complications of the disease. However, the scarcity of donated pancreata currently limits transplantation of the whole organ or of isolated pancreatic islets to a tiny fraction of those patients who might ben ...
STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Antivirals Targeting Flavivirus Envelope Proteins
SBC: L2 DIAGNOSTICS LLC Topic: N/ADESCRIPTION (provided by applicant): The overall goal of this project is to develop therapeutic antivirals to treat life-threatening flavivirus infections. Enfuvirtide, a clinically successful peptide HIV fusion inhibitor, is the prototype for a new class of antivirals that inhibit viral envelope protein structural rearrangements essential for viral entry into host cells. In preliminary experiment ...
STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
Automated Parkinson's Disease Dopamine Transporter Scan Analysis Fast Track
SBC: Molecular Neuroimaging, L.l.c. Topic: N/ADESCRIPTION (provided by applicant): We hypothesize that for a class of dopamine transporter SPECT agents, an automated software processing package can be developed, which will objectively yield striatal quantitative uptake values for evaluating Parkinson' s disease (PD) diagnosis and progression. This fully automated and Objective Striatal Analysis (OSA) package will be able to evaluate subjects ...
STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health -
Development of gene therapy product for treating MPS IIIB
SBC: NEUROGT INC Topic: 105Project Summary NeuroGT, Inc is a new start-up company founded by Dr. Haiyan Fu, Associate professor in the Gene Therapy Center at University of North Carolina at Chapel Hill, with the mission of develop and commercialize effective gene therapy products to treat rare neurogenetic diseases in humans. The goal of this project is to develop an effective gene therapy product targeting the root cause f ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Targeting STT3A and STT3B to Block Flavivirus Replication
SBC: New England Discovery Partners, LLC Topic: NIAIDAbstractMosquito borne flaviviruses cause disease worldwidewith members such as dengue virusDENVZika virusZIKVand west nile virusWNVinfecting more thanmillion individuals annuallyThe availability of small molecule antivirals that reduce flavivirus infection therefore could have an immediate and substantial impact on public health programs that seek to improve outcomes for populations infected with ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Vaccination against Zika virus infection using mosquito NeSt1 protein
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDArthropod-borne viruses (arboviruses) present a substantial threat to human and animal health worldwide. They are transmitted by hematophagous arthropods, in which mosquitoes are one of the main transmitters. The mosquito specie, Aedes aegypti, is the primary mosquito vector of several widely spread arboviruses as zika, dengue or West Nile viruses. Mosquitoes transmit these pathogens by inoculatin ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Development of Single Agent Antibiofilm Antibiotics
SBC: Synoxa Sciences, Inc Topic: NIAIDProject Summary Natural products have served as a productive source of drugs over the past decades and have represented, or been the inspiration for, a majority of antimicrobial compounds that have entered the clinic. The goal of this proposal is to develop novel antibacterial agents based on the marine natural product lipoxazolidinone A to treat recalcitrant Gram-positive infections. These scaffo ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Cell-penetrating antimicrobial therapeutics for treatment of complicated skin and soft tissue infections
SBC: TSRL, INC. Topic: NIAIDAbstract In the United Statesskin and soft tissue infectionsSSTIsare one of the most common indications for antibiotic treatmentrepresentingof hospital admissions andmillion doctor visits a yearSSTIs range from selflimiting furuncles and cellulitis to life threatening sepsis and tissue necrosisRecent studies suggest more thanof all SSTIs were caused by staphylococcal or streptococcal speciesin par ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development of Natural Product Inspired Adjuvants to Treat Tolerant Infections
SBC: Synoxa Sciences, Inc Topic: NIAIDProject Summary Natural products have served as a productive source of drugs over the past decades and have represented, or been the inspiration for, a majority of antimicrobial compounds that have entered the clinic. The goal of this proposal is to develop novel antibacterial adjuvants based on the marine natural product synoxazolidinone B to treat Gram-positive orthopedic joint infections. These ...
STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health -
Validation of a Diagnostic Test for Borrelia miyamotoi
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDABSTRACT Borrelia miyamotoi is a tick transmitted spirochete recently shown to cause infection and disease in the United StatesEurope and AsiaA member of the relapsing fever group of Borreliathis pathogen has been proven to cause most commonly a nonspecificflu like illness with feverfatiguemyalgiaand headacheDisease can be particularly severe and involve the central nervous system in immunocomprom ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health