Award Data

The overall goal of this proposed project (through Phase III) is to develop the Tacrolimus At-home Saliva Test (TAST) to measure tacrolimus at ng/mL levels in oral fluid (saliva) at-home in 15-20 minutes.  The TAST will replace the painful blood tests currently performed at hospital and clinics that military patients, who have limb, facial and organ transplants, must undergo to avoid transplant r ...

The National Commission on Military Aviation Safety determined that between 2013 and 2020, 224 lives, and 186 aircraft were lost due to military aviation mishaps amounting to losses of $11.6 billion. It is well documented that there is a negative impact on mission performance and an increased risk of accidents associated with sleep deprivation, extended time on intense attention demanding tasks, p ...

SEQUENTIAL SBIR PHASE II TECHNICAL OBJECTIVES AND APPROACH All activities of this proposed Sequential SBIR II are directed toward determining the incremental benefit of adding a metalloprotease inhibitor to varespladib for improving recovery and return to duty time following snakebite envenoming. The work will also advance the TRL of the metalloprotease inhibitor in order to support a SBIR III eff ...

In this proposed Phase II effort we will implement a software framework that will reduce the time required to annotate large image/video datasets by a factor of 100x while also reducing the data necessary to train state of the art computer vision models by up to 80%. Our strategy combines several elements and ideas. First, we have developed a sub-tile based a priori theory of how and why CNNs can ...

In Phase I we developed and demonstrated a bi-directional, monolithic, High-Speed, Electro-optic shutter for Range Gated Imaging. While meeting the majority of the key performance parameters for Range-Gated Imaging at high Pulse Repetition Frequency, improvements can be achieved in transmission, contrast and reliability. The Phase Ii activity begins with a upgraded Electro-optic Shutter incorpora ...

The Defense Health Agency seeks to develop a novel wearable wound infection treatment delivery device capable of delivering treatment for the prevention of infection in a prolonged care setting. Critical Innovations, NDA Partners, IOTAI, and consultants Loren Miller, MD, MPH, Gary Fong, PharmD, BCPS, BCIDP, Captain David Tanen, MD, FAAEM, FACMT (USN, Ret.), and former Commander Denise Whitfield, M ...

The purpose of this SBIR topic is to develop a device for automating needle decompression to more effectively manage tension pneumothorax on the battlefield.

The overall objective of the Phase II program is to develop and commercialize a portable, reliable, easy-to-use medical device called POMAS (Portable Oculomotor Multi-sensing Assessment System) (Figure 1) with associated software in order to enable non-invasive, fast, accurate and objective full spectrum oculomotor testing combined with 2 involuntary ANS (Autonomic Nervous System) measurements for ...

In order to address this urgent need, ChromoLogic LLC (CL) proposes to develop a ceramic membrane based portable oxygen generator (CEMPOG) to support the supply of medical grade oxygen for forward surgical teams. Unlike the regular membrane separation process, CEMPOG adopts mixed ionic–electronic conducting (MIEC) ceramic membrane to generate ultrapure O2 from ambient air, in which the oxygen mo ...

In order to meet the DoD’s need for a prophylactic medical countermeasure to reduce the risk of acute radiation syndrome (ARS) when taken before exposure to ionizing radiation, ChromoLogic proposes to develop multilamellar vesicle-encapsulation JP4-039 (JP4-039-MLV) as a radioprotector of ionizing radiation (IR)-induced health risks. DoD personnel, such as members of the Joint Forces, would self ...