Award Data

Methods for interconversion between cell types (cellular reprogramming) are currently discovered through resource intensive trial and error. Experiments may test a multitude of transcription factors to identify correct combinations that influence cell fate. In addition, reprogramming approaches commonly use stem cell intermediates such as induced pluripotent stem cells (iPSCs), which are generated ...

The broader impact/commercial potential of this Small Business Innovation Research Phase II project will combine computational protein engineering (CPE) software, tools and methods into a "platform technology" that enables new products and technologies in a wide range of scientific areas, including industrial enzymes, pharmaceuticals, therapeutics, medical diagnostics and bioenergy. This project w ...

We are proposing a new software framework for analyzing very large graphs using massively parallel processors (GPUs). This framework will be commercialized on a cloud platform that gives users immediate access to highly advanced big-data analytics through a user-friendly web interface, as well as an HTTP API for easy integration. The platform can be deployed on a private cloud if desired. The sy ...

This proposal is to extend into Phase II our development of a new system for Recognition of Communities and Heterogeneous Analysis of Group Interactions and Dynamics (RC-HAGID) for Social Media Forecasting. Social media enables groups, including terroris

It is desirable to make focal plane arrays (or imaging arrays) with reduced pitch; doing so enables smaller, cheaper and lighter camera systems that provide the same image resolution. Currently, the lower limit on pitch is set by electron/hole diffusion and light diffraction that results in crosstalk between neighboring pixels. Since electron hole pairs generated outside the depletion layer can ...

Obtaining situational awareness in tactical operations often involves high risk to personnel and/or equipment. The ELASTIC concept is to overcome this problem through the use of very low-cost, yet sophisticated, rapidly-deployable imaging sensors. Features of our proposed concept include use of highly portable equipment and support of a range of operational scenarios. Both of these features are ma ...

This Small Business Technology Transfer (STTR) Phase II project aims to develop commercially viable bacterial strains (Geobacter sulfurreducens) for use as biocatalysts in microbial fuel cells. The research genetically manipulates these bacteria to enable the utilization of alternative substrates and increase current generation through the expression of an energy consuming futile cycle. The rate ...

This Small Business Technology Transfer Research (STTR) Phase II project will complete the development of a support material for Ultrasonic Consolidation (UC) direct metal rapid prototyping and demonstrate the ability to build structures with high aspect ratios or overhanging features. This ability to apply UC to more complex shapes will enable engineers to design important parts more rapidly and ...